USO DO ÁCIDO URSODESOXICÓLICO NA PREVENÇÃO DA COLELITÍASE EM PACIENTES COM BYPASS GÁSTRICO EM Y DE ROUX: UMA REVISÃO

Introduction: Obesity is one of the biggest world health issues in current days; it results in the increasing prevalence of bariatric surgery. The gastric by-pass Roux-en-Y is one of the most performed surgeries for weight loss, however, it is associated with an elevated risk of cholelithiasis development. Objective: The study’s objective is evaluating the benefits of ursodeoxycholic acid versus to prophylaxis cholecystectomy for cholelithiasis prevention. Methodology: This study is a narrative revision of literature. The key words cholelithiasis; gastric by-pass; gastrectomy; ursodeoxycholic acid, were searched in the databases PubMed / Medline. Results: 13 articles were selected for analysis, wich the most recent was published in 2019 and the oldest in 2015. The type of studies accepted were cohort study, systematic reviews and metanalysis. Discussion: The preventive cholecystectomy and the post-bariatric offers risks and complications. The preventive use of UDCA significantly reduces the incidence of cholelithiasis post-bypass, besides that, it is well tolerate and has a smaller cost than cholecystectomy. Conclusion: The use of UDCA seems to be efficient for prevention of cholelithiasis and cholecystectomy postbypass, besides there are other advantages, as better costbenefit in comparison to other interventions.