与cpap治疗的睡眠呼吸暂停残留事件相关的因素:来自大型法国国家数据库的数据

S. Bailly, N. Daabek, I. Jullian-desayes, M. Joyeux-faure, M. Sapéne, Y. Grillet, J. Borel, R. Tamisier, J. Pépin
{"title":"与cpap治疗的睡眠呼吸暂停残留事件相关的因素:来自大型法国国家数据库的数据","authors":"S. Bailly, N. Daabek, I. Jullian-desayes, M. Joyeux-faure, M. Sapéne, Y. Grillet, J. Borel, R. Tamisier, J. Pépin","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2867","DOIUrl":null,"url":null,"abstract":"Introduction & background: Residual events during CPAP contribute to increase treatment drop-outs. Clinical scenarios triggering residual events during CPAP use are poorly described. Aims & objectives: Underlying comorbidities, especially cardiovascular diseases, lifestyle factors, OSA characteristics at baseline and type of mask are suggested as potential contributors. Methods: Patients from the prospective national French sleep apnea registry with apnea-hypopnea index (AHI) = 15/h and CPAP indication were included. A logistic regression analysis was used to identify factors associated with the probability of exhibiting a residual AHI > 5/h whilst on CPAP. Results: 12,285 OSA patients predominantly men (N=8715, 70.9%), middle aged (median [IQR]: 58.2 [49.8;66.1] years) and obese (median body mass index: 31.3 [27.7;35.6] kg/m²) were included. Most had an AHI=5/h (N=9,573, 77.9%) versus 22.1% exhibited an AHI>5/hour. The latter group was significantly less adherent to CPAP (5.75 [4.01;7.00] vs 6.00 [4.53;7.00] h/night). In multivariable analysis, factors associated with a high residual AHI were male gender, age and sedentary lifestyle, OSA severity, cardiovascular comorbidities and interface (orofacial versus nasal mask: OR = 2.15 [CI: 1.95;2.37]). Conclusions: The knowledge of at-risk clinical scenarios predicting more frequent residual events will help in the timely provision of personalized care including type of PAP therapy, attention to comorbidity care and interfacechoice","PeriodicalId":305670,"journal":{"name":"B30. SRN: BIG DATA ANALYSIS AND POPULATION BASED STUDIES","volume":"70 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Factors Associated with Residual Events in CPAP-Treated Sleep Apnea: Data from a Large French National Database\",\"authors\":\"S. Bailly, N. Daabek, I. Jullian-desayes, M. Joyeux-faure, M. Sapéne, Y. Grillet, J. Borel, R. Tamisier, J. Pépin\",\"doi\":\"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2867\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction & background: Residual events during CPAP contribute to increase treatment drop-outs. Clinical scenarios triggering residual events during CPAP use are poorly described. Aims & objectives: Underlying comorbidities, especially cardiovascular diseases, lifestyle factors, OSA characteristics at baseline and type of mask are suggested as potential contributors. Methods: Patients from the prospective national French sleep apnea registry with apnea-hypopnea index (AHI) = 15/h and CPAP indication were included. A logistic regression analysis was used to identify factors associated with the probability of exhibiting a residual AHI > 5/h whilst on CPAP. Results: 12,285 OSA patients predominantly men (N=8715, 70.9%), middle aged (median [IQR]: 58.2 [49.8;66.1] years) and obese (median body mass index: 31.3 [27.7;35.6] kg/m²) were included. Most had an AHI=5/h (N=9,573, 77.9%) versus 22.1% exhibited an AHI>5/hour. The latter group was significantly less adherent to CPAP (5.75 [4.01;7.00] vs 6.00 [4.53;7.00] h/night). In multivariable analysis, factors associated with a high residual AHI were male gender, age and sedentary lifestyle, OSA severity, cardiovascular comorbidities and interface (orofacial versus nasal mask: OR = 2.15 [CI: 1.95;2.37]). Conclusions: The knowledge of at-risk clinical scenarios predicting more frequent residual events will help in the timely provision of personalized care including type of PAP therapy, attention to comorbidity care and interfacechoice\",\"PeriodicalId\":305670,\"journal\":{\"name\":\"B30. SRN: BIG DATA ANALYSIS AND POPULATION BASED STUDIES\",\"volume\":\"70 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-04-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"B30. SRN: BIG DATA ANALYSIS AND POPULATION BASED STUDIES\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2867\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"B30. SRN: BIG DATA ANALYSIS AND POPULATION BASED STUDIES","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2867","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

介绍与背景:CPAP期间的残留事件会增加治疗退出率。在CPAP使用过程中引发残留事件的临床场景描述很少。目的和目的:潜在的合并症,特别是心血管疾病、生活方式因素、基线时的OSA特征和口罩类型被认为是潜在的影响因素。方法:纳入来自法国前瞻性全国睡眠呼吸暂停登记处的呼吸暂停低通气指数(AHI) = 15/h和CPAP指征的患者。采用逻辑回归分析来确定与CPAP时显示残余AHI bb0.5 /h的概率相关的因素。结果:纳入12285例OSA患者,以男性为主(N=8715, 70.9%),中年(中位[IQR]: 58.2[49.8;66.1]岁),肥胖(中位体重指数:31.3 [27.7;35.6]kg/m²)。大多数患者的AHI值为5/h (N= 9573, 77.9%), 22.1%患者的AHI值为5/h。后一组CPAP依从性明显较低(5.75 [4.01;7.00]vs 6.00 [4.53;7.00] h/夜)。在多变量分析中,与高残留AHI相关的因素包括男性性别、年龄和久坐生活方式、OSA严重程度、心血管合共病和界面(口面与鼻罩:OR = 2.15 [CI: 1.95;2.37])。结论:了解预测更频繁的残留事件的高危临床情景将有助于及时提供个性化护理,包括PAP治疗的类型、对合并症护理的关注和界面选择
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors Associated with Residual Events in CPAP-Treated Sleep Apnea: Data from a Large French National Database
Introduction & background: Residual events during CPAP contribute to increase treatment drop-outs. Clinical scenarios triggering residual events during CPAP use are poorly described. Aims & objectives: Underlying comorbidities, especially cardiovascular diseases, lifestyle factors, OSA characteristics at baseline and type of mask are suggested as potential contributors. Methods: Patients from the prospective national French sleep apnea registry with apnea-hypopnea index (AHI) = 15/h and CPAP indication were included. A logistic regression analysis was used to identify factors associated with the probability of exhibiting a residual AHI > 5/h whilst on CPAP. Results: 12,285 OSA patients predominantly men (N=8715, 70.9%), middle aged (median [IQR]: 58.2 [49.8;66.1] years) and obese (median body mass index: 31.3 [27.7;35.6] kg/m²) were included. Most had an AHI=5/h (N=9,573, 77.9%) versus 22.1% exhibited an AHI>5/hour. The latter group was significantly less adherent to CPAP (5.75 [4.01;7.00] vs 6.00 [4.53;7.00] h/night). In multivariable analysis, factors associated with a high residual AHI were male gender, age and sedentary lifestyle, OSA severity, cardiovascular comorbidities and interface (orofacial versus nasal mask: OR = 2.15 [CI: 1.95;2.37]). Conclusions: The knowledge of at-risk clinical scenarios predicting more frequent residual events will help in the timely provision of personalized care including type of PAP therapy, attention to comorbidity care and interfacechoice
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信