肺移植感染和排斥反应的早期发现

S. M. Finkelstein, Marshall I. Hertz, M. Snyder, C. Edin, C. Wielinski, Bruce R. Lindgren, B. Prasad, W. Warwick
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引用次数: 7

摘要

一种无纸化电子日记/肺活量计仪器已在进行肺移植的受试者的家庭监测计划中进行了测试。该计划的目标是提供感染或排斥反应的早期检测,以便在潜在临床问题的最早迹象中制定治疗干预措施。本研究报告了家庭监测项目的早期检测能力,重点是慢性排斥反应(OB)和感染(CMV)的例子。在临床诊断感染或排斥反应前30-90天,家庭数据中肺活量下降和呼吸道症状增加。因此,家庭监测可以为肺移植术后感染或排斥反应的早期检测提供一种方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Early detection of infection and rejection in lung transplantation
A paperless electronic diary/spirometer instrument has been tested in a home monitoring program for subjects who have undergone lung transplantation. The objective of the program is to provide early defection of infection or rejection so that therapeutic intervention can be instituted at the earliest sign of potential clinical problems. This study reports on the early detection capability of the home monitoring program, focusing on example cases of chronic rejection (OB) and infection (CMV). Declines in spirometry and increases in respiratory symptoms appeared in the home data 30-90 days before infection or rejection diagnoses were made in clinic. Thus home monitoring can provide a method for the early detection of infection or rejection after lung transplantation.<>
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