分子包如何改善细胞间的通讯

Proceedings of the Eight Annual ACM International Conference on Nanoscale Computing and Communication Pub Date : 2021-09-07 DOI:10.1145/3477206.3477469

F. Pappalardo, N. Iraci, L. Leggio, A. Lombardo, G. Morabito

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引用次数: 0

摘要

细胞可以通过多种方式进行交流。除了细胞通信的经典途径外，细胞外囊泡(ev)可以携带不同性质的大分子(DNA, RNA，蛋白质等)，因此它们可以与携带信息的数据包相比较，这些数据包可以同时刺激靶细胞内的不同分子途径。在本文中，提出了一个模型来评估通过ev的细胞间通讯的效率，相对于经典的配体-受体途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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How molecular packets improve cell-to-cell communication

Cells can communicate in multiple ways. Alongside the classic pathways of cellular communication, Extracellular Vesicles (EVs), can carry macromolecules of different nature (DNA, RNA, proteins, etc.) and thus they can be compared to packets carrying information that concur to stimulate different molecular pathways within the target cell. In this paper a model is proposed that evaluates the higher efficiency of cell-to-cell communication via EVs with respect to the classical ligand-receptor pathway.

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Proceedings of the Eight Annual ACM International Conference on Nanoscale Computing and Communication

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