用酶和化学方法修饰蛋白质和聚氨基酸

Biopolymers Online Pub Date : 2002-12-09 DOI:10.1002/3527600035.BPOL7015

K. Ohkawa, Hiroyuki Yamamoto

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引用次数: 2

摘要

天然交联材料角蛋白、胶原蛋白、无脊椎动物体内细胞蛋白的异肽交联参与蛋白质交联的酶赖氨酸氧化酶酪氨酸酶转谷氨酰胺酶化学交联双功能交联试剂氧化剂光诱导交联多肽侧链的光二聚化非共价交联静电力相互作用交联蛋白和聚氨基酸交联水凝胶多离子复合物材料科学关键词:交联反应;双功能试剂;酶;多肽;材料科学

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Modifications of Proteins and Poly(amino acids) by Enzymatic and Chemical Methods

Introduction Naturally Occurring Cross-linked Materials Keratin, Collagen, and Elastin Structural Proteins in Invertebrate Bodies Isopeptide Cross-linking of Cellular Proteins Enzymes Involved in the Protein Cross-links Lysyl Oxidase Tyrosinase Transglutaminase Chemical Cross-linking Bifunctional Cross-linking Reagents Oxidants Photo-Induced Cross-linking – Photodimerization of Polypeptide Side Chain Noncovalent Cross-linking – Electrostatic Force Interaction Material Science of Cross-linked Proteins and Poly(amino acids) Cross-linked Hydrogels Polyion Complex Material Formulations Medical Adhesives Outlook and Perspectives Acknowledgments Keywords: cross-linking reactions; bifunctional reagents; enzymes; polypeptides; material science

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Biopolymers Online

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