孤立性右束支传导阻滞患者右心室形态学特征及功能

S. Murtuza, S. Regmi, B. Dhital, S. Thapa, P. Gurung, A. Khan, Sagar Thapa
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摘要

背景:右束支传导阻滞(RBBB)的患病率估计为0.2%至1.3%的健康人。RBBB与右心室(RV)功能下降有独立的相关性,这被认为是不良心血管结局的预测因子。本研究的目的是利用二维超声心动图评估孤立性RBBB(无结构性心脏病)患者的右心室结构和功能。方法:一项横断面研究于2022年1月1日至2022年6月30日在Chitwan Medical College, Bharatpur进行。年龄≥18岁孤立性RBBB的连续成人患者根据心电图表现分为完全RBBB (CRBBB)和不完全RBBB (IRBBB)。超声心动图评价右心室的尺寸和功能。结果:共纳入52例孤立性RBBB患者,研究人群平均年龄为45.3±9.3岁,其中CRBBB (28.53.8%), IRBBB(24.46.2%)。在评价RV功能的参数中;CRBBB组的平均心室面积变化(P<0.001)、三尖瓣环平面收缩偏移(P<0.02)和左心室外侧环脉冲多普勒峰值速度(P<0.001)显著低于IRBBB组,而脉冲多普勒心肌功能指数(P<0.001)显著高于IRBBB组。与IRBBB组相比,CRBBB组右心房和右心室尺寸参数明显升高。结论:离体RBBB不像想象的那样是良性的,对右心室形态和功能的影响越来越差。因此,孤立性RBBB患者需要随着年龄的增长进行随访,并更多地关注右心室的结构和功能分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
MORPHOLOGIC CHARACTERISTICS AND FUNCTION OF RIGHT VENTRICLE IN PATIENTS WITH ISOLATED RIGHT BUNDLE BRANCH BLOCK
Background: The prevalence of right bundle branch block (RBBB) is estimated in 0.2 to 1.3% of healthy people. RBBB had independent association with decreased right ventricle (RV) function, which is considered as predictor of adverse cardiovascular outcomes. The aim of this study is to evaluate RV structure and function in patients with isolated RBBB (without structural heart disease) using two-dimensional echocardiography. Methods: A cross-sectional study conducted at Chitwan Medical College, Bharatpur from 1st January 2022 to 30th June 2022. Consecutive adult patients aged ≥18 years with isolated RBBB classified into complete RBBB (CRBBB) and Incomplete RBBB (IRBBB) based on electrocardiographic findings. The echocardiographic evaluation was done to assess RV dimension and function. Results: A total of 52 patients with isolated RBBB were included with mean age of the study population was 45.3 ± 9.3 years, (28 ,53.8%) had CRBBB, whereas the remaining (24, 46.2%) had IRBBB. Among the parameters used to assess RV function; mean RV-Fractional area change (P<0.001), Tricuspid annular plane systolic excursion(P<0.02) and Pulsed Doppler peak velocity at the lateral annulus RV(P<0.001) were significantly lower, while Pulsed Doppler myocardial performance index(P<0.001) was significantly high in CRBBB group as compared to IRBBB group. Similarly, Right atrium and RV dimensional parameters were significant higher in CRBBB compared to IRBBB group. Conclusions: Isolated RBBB is not as benign as it was considered and has deteriorating effect on RV morphology and function. Therefore, patients with Isolated RBBB need follow-up with passing age and more attention toward RV structural and functional analysis.
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