生姜提取物的药理作用热固化丙烯酸树脂板上的白色念珠菌

Gina Nada Maulidya, T. Widodo, Tahta Danifatis Sunnah
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摘要

背景:牙科中常用的义齿基托是热固化聚甲基丙烯酸甲酯树脂或热聚合丙烯酸树脂。丙烯酸树脂有一个弱点,即丙烯酸树脂的表面会引发细菌和白色念珠菌的生长。白色念珠菌在义齿口炎的发生中起重要作用。流行病学研究表明,假牙口腔炎的患病率相当高,在假牙使用者中占30%-50%。抑制白色念珠菌在丙烯酸树脂上的生长需要创新,其中之一是生姜提取物的使用。生姜可以抗真菌,因为它含有酚类物质和精油。目的:研究生姜提取物对热固化丙烯酸树脂中白色念珠菌的抑制作用。方法:本研究设计为单纯后验对照组设计,共24个样本。治疗组3个,对照组1个。统计检验采用单因素方差分析Welch和事后Games-Howell检验。结果:25%和50%生姜提取物对热固化丙烯酸树脂的白色念珠菌有显著的抑制作用。Shapiro-Wilk检验结果为正态,同质性检验结果为非同质。采用事后Games-Howell的单向方差分析Welch进行分析检验,结果显示4个实验组之间存在显著差异。结论:25%和50%生姜提取物对热固化丙烯酸树脂的白色念珠菌抑制效果显著,平均真菌数分别为2和1。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
EFFECT OF GINGER EXTRACT (ZINGIBER OFCINALE ROSC.) ON CANDIDA ALBICANS ON HEAT CURED ACRYLIC RESIN PLATE
Background: Denture bases that are often used in dentistry are heat cured polymethyl methacrylate acrylic resin or heat polymerized acrylic resin. Acrylic resin has a weakness, namely the surface of the acrylic resin that can trigger the growth of bacteria and Candida albicans. Candida albicans has an important role in the occurrence of denture stomatitis. Epidemiological studies show the prevalence of denture stomatitis is quite high, ranging from 30%-50% in denture users. Innovation is needed to inhibit the growth of Candida albicans on acrylic resin, one of which is the use of ginger extract. Ginger can be antifungal because of the content of phenols and essential oils. Objective: To determine the effect of ginger extract (Zingiber ofcinale Rosc.) on Candida albicans on heat cured acrylic resin. Methods: This research design was a post test only control group design with a total sample of 24 samples. There was 3 treatment groups and 1 control group. Statistical test used One-way ANOVA Welch with post hoc Games-Howell test. Results: The results showed that there was a significant effect of 25% and 50% ginger extract on Candida albicans on heat cured acrylic resin. The Shapiro-Wilk test got normal results and the homogeneity test got inhomogeneous results. The analytic test conducted used One-way ANOVA Welch with post hoc Games-Howell and the result showed a significant differences in the 4 test groups Conclusion: There was a significant effect of 25% and 50% ginger extract in inhibiting Candida albicans on heat cured acrylic resin with an average fungal count of 2 and 1.
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