{"title":"黑麻igkappa基因与人免疫球蛋白kappa基因座的整体鉴定。无脊椎动物igkappa基因研究的新进展","authors":"","doi":"10.46545/aijcs.v2i1.199","DOIUrl":null,"url":null,"abstract":"Entiere identities between Invertebrate Ophiocomina nigra IGKappa gene and Human IGK gene are confirmed, in the present work, at the level of immunoglobulin domains (constant and variable). The transcriptome of the Ophuirid : Ophiocomina nigra IGKappa gene was discovered recently(1).Since it was synthesized de novo and cloned in a pUC-GW-Kan plasmid (2) which was a gift of Bo Huang laboratories. The original sequence of the IGKappa gene, after cloning, was the following in 5’-3’ :","PeriodicalId":262551,"journal":{"name":"American International Journal of Cancer Studies","volume":"17 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ENTIERE IDENTITIES BETWEEN OPHIOCOMINA NIGRA IGKAPPA GENE AND HUMAN IMMUNOGLOBULIN KAPPA LOCUS.NEW ASPECTS OF INVERTEBRATE IGKAPPA GENES (IPA)\",\"authors\":\"\",\"doi\":\"10.46545/aijcs.v2i1.199\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Entiere identities between Invertebrate Ophiocomina nigra IGKappa gene and Human IGK gene are confirmed, in the present work, at the level of immunoglobulin domains (constant and variable). The transcriptome of the Ophuirid : Ophiocomina nigra IGKappa gene was discovered recently(1).Since it was synthesized de novo and cloned in a pUC-GW-Kan plasmid (2) which was a gift of Bo Huang laboratories. The original sequence of the IGKappa gene, after cloning, was the following in 5’-3’ :\",\"PeriodicalId\":262551,\"journal\":{\"name\":\"American International Journal of Cancer Studies\",\"volume\":\"17 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American International Journal of Cancer Studies\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46545/aijcs.v2i1.199\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American International Journal of Cancer Studies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46545/aijcs.v2i1.199","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
在目前的工作中，在免疫球蛋白结构域(恒定和可变)水平上，证实了无脊椎动物黑麻IGKappa基因与人类IGK基因之间的整体一致性。Ophuirid: Ophiocomina nigra IGKappa基因的转录组是最近发现的(1)。由于它是从头合成并克隆在黄渤实验室赠送的pucc - gw - kan质粒(2)上。IGKappa基因克隆后的原始序列为5′-3′:
ENTIERE IDENTITIES BETWEEN OPHIOCOMINA NIGRA IGKAPPA GENE AND HUMAN IMMUNOGLOBULIN KAPPA LOCUS.NEW ASPECTS OF INVERTEBRATE IGKAPPA GENES (IPA)
Entiere identities between Invertebrate Ophiocomina nigra IGKappa gene and Human IGK gene are confirmed, in the present work, at the level of immunoglobulin domains (constant and variable). The transcriptome of the Ophuirid : Ophiocomina nigra IGKappa gene was discovered recently(1).Since it was synthesized de novo and cloned in a pUC-GW-Kan plasmid (2) which was a gift of Bo Huang laboratories. The original sequence of the IGKappa gene, after cloning, was the following in 5’-3’ :
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