An MRI/CT-based cardiac electroanatomical mapping system with scattered data interpolation algorithm

In this paper we are proposing an MRI/CT-guided cardiac electroanatomical mapping system, EpreMap. EpreMap was developed as an extension to the guidance system developed at King's College London for cardiac electrophysiology procedures. This platform allows for both the registration of MRI/CT anatomical data to X-ray fluoroscopy and the determination of the catheter positions. EpreMap is a contact mapping system. By using a radial basis function (RBF) based scattered data interpolation algorithm, EpreMap can create a cardiac activation map for a whole chamber starting from five sampling points. The activation map is updated with every new measurement. Offline studies showed that cardiac activation maps created by using EpreMap were highly correlated with the maps created by using a non-contact mapping system. EpreMap was used in three clinical cases. The clinical studies proved the workflow of EpreMap was valid in the clinical environment. For one clinical case, the result of EpreMap was validated against a non-contact mapping system. Clinically significant regions identified by using the two mapping systems were strongly correlated.