Hazem El-Akabawy , Hamdy Abdul Azeem , EL-Shazly Abdul Khalek
{"title":"经皮冠状动脉介入治疗缺血性二尖瓣反流的短期疗效","authors":"Hazem El-Akabawy , Hamdy Abdul Azeem , EL-Shazly Abdul Khalek","doi":"10.1016/j.ejccm.2018.02.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>The effect of revascularization by PCI for acute coronary syndrome (ACS) on the severity of ischemic mitral regurge (IMR) is still unclear.</p></div><div><h3>Objective</h3><p>To evaluate the effect of successful total revascularization by PCI for ACS on the degree of IMR.</p></div><div><h3>Methods</h3><p>A total of 240 patients presenting with ACS for the first time were studied by this an open-label, multicenter, prospective clinical trial between July 2015 to February 2017. All patients were subjected for clinical assessment, transthoracic echocardiographic assessment and coronary angiography. The patients divided into two groups: <strong>group A</strong>; those who had undergone successful total revascularization of a significant coronary artery disease using PCI, and <strong>group B</strong>; those who had optimal medical treatment with no total revascularization, failed PCI or for CABG. <strong>Group A</strong> patients subdivided into <strong>subgroup I</strong>, patients with improvement of the IMR; and <strong>subgroup II</strong>, patients with no improvement of IMR.</p></div><div><h3>Results</h3><p>Only 65% of the patients showed IMR and 149 of them underwent successful complete revascularization by PCI; 68% of them showed IMR improvement and 32% showed no improvement. There was a significant improvement of the IMR degree after total revascularization by PCI. Moreover, this improvement was significant in subgroup I (p < 0.001). Percutaneous coronary intervention, EF and SWMI were significant predictors of IMR improvement following successful complete revascularization.</p></div><div><h3>Conclusion</h3><p>Successful total revascularization by early PCI improve IMR degree.</p></div>","PeriodicalId":31233,"journal":{"name":"Egyptian Journal of Critical Care Medicine","volume":null,"pages":null},"PeriodicalIF":0.3000,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ejccm.2018.02.001","citationCount":"2","resultStr":"{\"title\":\"Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation\",\"authors\":\"Hazem El-Akabawy , Hamdy Abdul Azeem , EL-Shazly Abdul Khalek\",\"doi\":\"10.1016/j.ejccm.2018.02.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>The effect of revascularization by PCI for acute coronary syndrome (ACS) on the severity of ischemic mitral regurge (IMR) is still unclear.</p></div><div><h3>Objective</h3><p>To evaluate the effect of successful total revascularization by PCI for ACS on the degree of IMR.</p></div><div><h3>Methods</h3><p>A total of 240 patients presenting with ACS for the first time were studied by this an open-label, multicenter, prospective clinical trial between July 2015 to February 2017. All patients were subjected for clinical assessment, transthoracic echocardiographic assessment and coronary angiography. The patients divided into two groups: <strong>group A</strong>; those who had undergone successful total revascularization of a significant coronary artery disease using PCI, and <strong>group B</strong>; those who had optimal medical treatment with no total revascularization, failed PCI or for CABG. <strong>Group A</strong> patients subdivided into <strong>subgroup I</strong>, patients with improvement of the IMR; and <strong>subgroup II</strong>, patients with no improvement of IMR.</p></div><div><h3>Results</h3><p>Only 65% of the patients showed IMR and 149 of them underwent successful complete revascularization by PCI; 68% of them showed IMR improvement and 32% showed no improvement. There was a significant improvement of the IMR degree after total revascularization by PCI. Moreover, this improvement was significant in subgroup I (p < 0.001). Percutaneous coronary intervention, EF and SWMI were significant predictors of IMR improvement following successful complete revascularization.</p></div><div><h3>Conclusion</h3><p>Successful total revascularization by early PCI improve IMR degree.</p></div>\",\"PeriodicalId\":31233,\"journal\":{\"name\":\"Egyptian Journal of Critical Care Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2018-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.ejccm.2018.02.001\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Egyptian Journal of Critical Care Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S209073031830001X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Egyptian Journal of Critical Care Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S209073031830001X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
Short-term effect of percutaneous coronary intervention on ischemic mitral regurgitation
Background
The effect of revascularization by PCI for acute coronary syndrome (ACS) on the severity of ischemic mitral regurge (IMR) is still unclear.
Objective
To evaluate the effect of successful total revascularization by PCI for ACS on the degree of IMR.
Methods
A total of 240 patients presenting with ACS for the first time were studied by this an open-label, multicenter, prospective clinical trial between July 2015 to February 2017. All patients were subjected for clinical assessment, transthoracic echocardiographic assessment and coronary angiography. The patients divided into two groups: group A; those who had undergone successful total revascularization of a significant coronary artery disease using PCI, and group B; those who had optimal medical treatment with no total revascularization, failed PCI or for CABG. Group A patients subdivided into subgroup I, patients with improvement of the IMR; and subgroup II, patients with no improvement of IMR.
Results
Only 65% of the patients showed IMR and 149 of them underwent successful complete revascularization by PCI; 68% of them showed IMR improvement and 32% showed no improvement. There was a significant improvement of the IMR degree after total revascularization by PCI. Moreover, this improvement was significant in subgroup I (p < 0.001). Percutaneous coronary intervention, EF and SWMI were significant predictors of IMR improvement following successful complete revascularization.
Conclusion
Successful total revascularization by early PCI improve IMR degree.
期刊介绍：
The Egyptian Journal of Critical Care Medicine is the official Journal of the Egyptian College of Critical Care Physicians, the most authoritative organization of Egyptian physicians involved in the multi-professional field of critical care medicine. The journal is intended to provide a peer-reviewed source for multidisciplinary coverage of general acute and intensive care medicine and its various subcategories including cardiac, pulmonary, neuro, renal as well as post-operative care. The journal is proud to have an international multi-professional editorial board in the broad field of critical care that will assist in publishing promising research and breakthrough reports that lead to better patients care in life threatening conditions, and bring the reader a quick access to the latest diagnostic and therapeutic approaches in monitoring and management of critically ill patients.
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