В. А. Державин, В. Ю. Карпенко, А. В. Бухаров, М. В. Иванова
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There were 14 men (54%), women 12 (46%). Patients with primary malignant tumors of bones 23 (88%) prevailed among patients. Depending on the morphological structure, 16 (61%) had chondrosarcoma, 4 (15%) had osteosarcoma and 3 (11%) had a malignant fibrous histiocytoma. Three (11%) patients had locally advanced softtissue sarcomas. In 2 (7.5%) synovial sarcoma and in one (3.5%) malignant tumor from the shells of peripheral nerves. The primary tumor process was in 21 (81%) patients. The clinical stage was established as IIb in 14 (54%), Ib in 3 (11%), IVa 1 (3.5%) and IVb in 3 (11%) patients, respectively. Results. The average duration of the operation was 4.1 hours (2.7–6 hours). The volume of intraoperative blood loss is 3400 ml (500–9000 ml). The margin of resection was evaluated as positive in 4 (15%) patients. The recurrence of the tumor after the IIAD performed by us was in 4 (15%) patients with a negative edge of R0 resection. Conclusions. Postoperative complications were noted in 5 (19%) patients. Four (80%) had wound purulent-septic com-plications: partial flap necrosis — 2, total necrosis of the flap — 1, edge necrosis of the wound — 1 patient. The overall 5-year survival rate of patients treated in the clinic by the treatment was 40%. The results of the functional status of patients after the operation were 45% on the MSTS scale, which correlates with the data of other authors.","PeriodicalId":119961,"journal":{"name":"Research'n Practical Medicine Journal","volume":"20 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"МЕЖПОДВЗДОШНО-БРЮШНОЕ ВЫЧЛЕНЕНИЕ В ЛЕЧЕНИИ БОЛЬНЫХ С МЕСТНОРАСПРОСТРАНЕННЫМИ САРКОМАМИ КОСТЕЙ И МЯГКИХ ТКАНЕЙ\",\"authors\":\"В. А. Державин, В. Ю. Карпенко, А. В. Бухаров, М. В. Иванова\",\"doi\":\"10.17709/2409-2231-2018-5-1-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Inter-ileal abdominal dissection (IIAD) is one of the most traumatic maiming operations, which implies removal of the lower limb with a single block with an adjacent half of the pelvic ring. Taking into account the low overall incidence of locally advanced bony and soft tissue sarcomas localized in the projection of the pelvic bone and hip joints, and a small number of clinics with sufficient experience in performing such operations, modern specialized literature has a limited number of publications on the IIAD. Purpose. Presentation of the experience in the implementation of the IIAD in patients with locally advanced sarcomas of bones and soft tissues. Patients and methods . The analysis of results of treatment of 26 patients with locally advanced sarcomas of bones and soft tissues is presented. There were 14 men (54%), women 12 (46%). Patients with primary malignant tumors of bones 23 (88%) prevailed among patients. Depending on the morphological structure, 16 (61%) had chondrosarcoma, 4 (15%) had osteosarcoma and 3 (11%) had a malignant fibrous histiocytoma. Three (11%) patients had locally advanced softtissue sarcomas. In 2 (7.5%) synovial sarcoma and in one (3.5%) malignant tumor from the shells of peripheral nerves. The primary tumor process was in 21 (81%) patients. The clinical stage was established as IIb in 14 (54%), Ib in 3 (11%), IVa 1 (3.5%) and IVb in 3 (11%) patients, respectively. Results. The average duration of the operation was 4.1 hours (2.7–6 hours). The volume of intraoperative blood loss is 3400 ml (500–9000 ml). The margin of resection was evaluated as positive in 4 (15%) patients. The recurrence of the tumor after the IIAD performed by us was in 4 (15%) patients with a negative edge of R0 resection. Conclusions. Postoperative complications were noted in 5 (19%) patients. Four (80%) had wound purulent-septic com-plications: partial flap necrosis — 2, total necrosis of the flap — 1, edge necrosis of the wound — 1 patient. The overall 5-year survival rate of patients treated in the clinic by the treatment was 40%. 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引用次数: 0
摘要
回肠间腹腔剥离术(IIAD)是最具创伤性的致残手术之一,它意味着切除下肢与邻近的一半骨盆环。考虑到局限于骨盆骨和髋关节突出部位的局部晚期骨和软组织肉瘤的总体发病率较低,以及有足够经验进行此类手术的诊所数量较少,现代专业文献中关于IIAD的出版物数量有限。目的。介绍在局部晚期骨和软组织肉瘤患者中实施IIAD的经验。患者和方法。本文对26例局部晚期骨软组织肉瘤的治疗结果进行了分析。男性14人(54%),女性12人(46%)。原发性骨恶性肿瘤患者23例(88%)。根据形态学结构,16例(61%)为软骨肉瘤,4例(15%)为骨肉瘤,3例(11%)为恶性纤维组织细胞瘤。3例(11%)患者有局部晚期软组织肉瘤。2例(7.5%)滑膜肉瘤,1例(3.5%)周围神经外壳恶性肿瘤。21例(81%)患者发生原发肿瘤。临床分期分别为IIb 14例(54%)、Ib 3例(11%)、IVa 1例(3.5%)和IVb 3例(11%)。结果。手术时间平均4.1小时(2.7 ~ 6小时)。术中出血量3400 ml (500-9000 ml)。4例(15%)患者的切除边缘评估为阳性。我们所做的IIAD术后肿瘤复发率为4(15%)例R0切除阴性边缘患者。结论。5例(19%)患者出现术后并发症。4例(80%)有伤口脓毒性并发症:皮瓣部分坏死2例,皮瓣全坏死1例,伤口边缘坏死1例。经临床治疗的患者5年总生存率为40%。术后患者的功能状态在MSTS量表上的评分为45%,与其他作者的数据相关。
МЕЖПОДВЗДОШНО-БРЮШНОЕ ВЫЧЛЕНЕНИЕ В ЛЕЧЕНИИ БОЛЬНЫХ С МЕСТНОРАСПРОСТРАНЕННЫМИ САРКОМАМИ КОСТЕЙ И МЯГКИХ ТКАНЕЙ
Inter-ileal abdominal dissection (IIAD) is one of the most traumatic maiming operations, which implies removal of the lower limb with a single block with an adjacent half of the pelvic ring. Taking into account the low overall incidence of locally advanced bony and soft tissue sarcomas localized in the projection of the pelvic bone and hip joints, and a small number of clinics with sufficient experience in performing such operations, modern specialized literature has a limited number of publications on the IIAD. Purpose. Presentation of the experience in the implementation of the IIAD in patients with locally advanced sarcomas of bones and soft tissues. Patients and methods . The analysis of results of treatment of 26 patients with locally advanced sarcomas of bones and soft tissues is presented. There were 14 men (54%), women 12 (46%). Patients with primary malignant tumors of bones 23 (88%) prevailed among patients. Depending on the morphological structure, 16 (61%) had chondrosarcoma, 4 (15%) had osteosarcoma and 3 (11%) had a malignant fibrous histiocytoma. Three (11%) patients had locally advanced softtissue sarcomas. In 2 (7.5%) synovial sarcoma and in one (3.5%) malignant tumor from the shells of peripheral nerves. The primary tumor process was in 21 (81%) patients. The clinical stage was established as IIb in 14 (54%), Ib in 3 (11%), IVa 1 (3.5%) and IVb in 3 (11%) patients, respectively. Results. The average duration of the operation was 4.1 hours (2.7–6 hours). The volume of intraoperative blood loss is 3400 ml (500–9000 ml). The margin of resection was evaluated as positive in 4 (15%) patients. The recurrence of the tumor after the IIAD performed by us was in 4 (15%) patients with a negative edge of R0 resection. Conclusions. Postoperative complications were noted in 5 (19%) patients. Four (80%) had wound purulent-septic com-plications: partial flap necrosis — 2, total necrosis of the flap — 1, edge necrosis of the wound — 1 patient. The overall 5-year survival rate of patients treated in the clinic by the treatment was 40%. The results of the functional status of patients after the operation were 45% on the MSTS scale, which correlates with the data of other authors.