代谢途径双目标优化的迭代策略

2011 Fourth International Joint Conference on Computational Sciences and Optimization Pub Date : 2011-04-15 DOI:10.1109/CSO.2011.83

Gongxian Xu

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引用次数: 2

摘要

本文提出了一种迭代策略来解决代谢途径的双目标优化问题。代谢系统首先用s系统形式主义来表示。然后采用迭代加权和方法，使代谢途径的性能最大化，同时使其成本最小化。将所提出的迭代策略应用于酿酒酵母的发酵途径，并证明了该方法的有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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An Iterative Strategy for Bi-objective Optimization of Metabolic Pathways

This paper proposes an iterative strategy to address the bi-objective optimization of metabolic pathways. The metabolic system is firstly represented by the S-system formalism. Then a weighted-sum method is used iteratively to maximize the performance of a metabolic pathway while minimizing its cost. The presented iterative strategy is applied to the fermentation pathway in Saccharomyces cerevisiae and shown to the effectiveness of the approach.

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2011 Fourth International Joint Conference on Computational Sciences and Optimization

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