放射性核素在健康和疾病脑扫描中的作用综述

Journal of Neurology and Stroke Pub Date : 2017-04-17 DOI:10.15406/JNSK.2017.06.00211

Sanjoy Sanyal

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引用次数: 0

摘要

99mTc高锝酸盐扫描:高锝酸盐(Tc)中的高锝酸盐(TcO4)离子与血浆蛋白结合，迅速移动到细胞外空间，并由于血脑屏障(BBB)的存在，像氯离子(Cl-)一样分布在除正常脑外的各种器官中。因此，与其他器官不同，正常大脑对同位素的吸收可以忽略不计，这阻碍了同位素扫描对其的有效可视化[3]。

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Overview of Role of Radionuclides in Scanning the Brain in Health and Disease

99mTc pertechnetate scan: The pertechnetate (TcO4) ion in technetium (Tc) pertechnetate binds to plasma proteins, quickly moves into the extra-cellular space and distributes itself like the chloride (Cl-) ion in various organs except the normal brain because of the blood brain barrier (BBB). Thus, negligible uptake of the isotope by the normal brain prevents its effective visualisation by isotope scan, unlike other organs [3].

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Journal of Neurology and Stroke

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