基于核Adatron进化算法训练的支持向量机用于大规模蛋白质结构分类

N. Arana-Daniel, Alberto A. Gallegos, C. López-Franco, A. Alanis, J. Morales, Adriana Lopez-Franco
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引用次数: 11

摘要

随着计算机功能的不断增强,可以在短时间内处理的数据量呈指数级增长,对大规模数据进行有效分类的重要性也随之增加。支持向量机在蛋白质结构预测、垃圾邮件识别、医学诊断、光学字符识别、文本分类等产生的大量高维数据中显示出良好的分类效果。大多数用于大规模学习的最先进的方法使用传统的优化方法,如二次规划或梯度下降,这使得使用进化算法来训练支持向量机成为一个有待探索的领域。本文提出了一种基于进化算法和Kernel-Adatron的简单实现方法来解决大规模分类问题,重点关注蛋白质结构预测。蛋白质的功能特性取决于它们的三维结构。了解蛋白质的结构对生物学至关重要,并可能导致医学、农业和生物燃料等领域的进步。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Support Vector Machines Trained with Evolutionary Algorithms Employing Kernel Adatron for Large Scale Classification of Protein Structures
With the increasing power of computers, the amount of data that can be processed in small periods of time has grown exponentially, as has the importance of classifying large-scale data efficiently. Support vector machines have shown good results classifying large amounts of high-dimensional data, such as data generated by protein structure prediction, spam recognition, medical diagnosis, optical character recognition and text classiffication, etc. Most state of the art approaches for large-scale learning use traditional optimization methods, such as quadratic programming or gradient descent, which makes the use of evolutionary algorithms for training support vector machines an area to be explored. The present paper proposes an approach that is simple to implement based on evolutionary algorithms and Kernel-Adatron for solving large-scale classiffication problems, focusing on protein structure prediction. The functional properties of proteins depend upon their three-dimensional structures. Knowing the structures of proteins is crucial for biology and can lead to improvements in areas such as medicine, agriculture and biofuels.
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