维持性血液透析患者的分析性高血压频率:单中心研究

Dr. Marium Mobasshera, Dr. Md. Ahsan Zayeed, D. K. Naher
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摘要

慢性肾脏疾病是一个全球性的公共卫生问题。在世界范围内,大多数可以接受肾脏替代治疗的终末期肾病(ESRD)患者正在接受血液透析(HD)。血液透析不是一个顺利的过程。它有几个并发症;溶性高血压(IDH)就是其中之一。该研究的目的是确定血液透析患者中分析性高血压的频率。方法:这项前瞻性观察性研究于2021年11月至2022年4月在孟加拉国达卡国家肾脏疾病和泌尿科研究所进行。该研究共纳入249例患者。采用方便的目的抽样方法。结果:年龄小于20岁的患者仅有5例(2%),年龄大于60岁的患者有28例(11.2%)。半数患者为女性(127.51%),半数患者为男性。只有15例(6%)患者有透析内HTN。透析前、透析后和透析内的平均血压分别为102.78±SD、62±SD和81.74±SD。透析期间超滤平均值为2789±SD。透析期间平均血流量为235.17±SD。IDH与超滤、IDH与体重变化呈弱正相关,且不显著。血中HTN与血流量的关系较弱,呈负相关,不显著。结论:分析性高血压是我国观察到的最重要的血液透析困难,体重增加和超滤注意力高的受试者发生高血压的风险更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Frequency of Intradialytic Hypertension among Maintenance Hemodialysis Patients: A Single Centre Study
Introduction: Chronic kidney disease is a public health problem around the world. Worldwide, most patients with end-stage renal disease (ESRD) who can access renal replacement therapy are receiving hemodialysis (HD).Hemodialysis is not a smooth process. It has several complications; intradialytic hypertension (IDH) is one of them.The aim of the study was to determine the frequency of intradialytic hypertension among hemodialysis patients. Methods: This prospective observational study was conducted at the National Institute of kidney diseases and urology, Dhaka, Bangladesh from November 2021 to April 2022. A total of 249 patients were included in the study. A convenient purposive sampling method was used. Results: Only 5(2%) patients received HD whose age was less than 20 and 28 (11.2%) patients were aged more than 60 years of age. Half of the patients were female (127, 51%) and half of the patients were male. Only 15 patients (6%) population had Intra dialytic HTN. Pre-Dialytic, Post-Dialytic, and Intra- dialytic mean blood pressure was 102.78±SD, 62±SD, and 81.74±SD, respectively. Mean ultrafiltration during dialysis was 2789±SD. Mean blood flow during dialysis was 235.17±SD. The relationship between IDH and ultrafiltration and IDH and weight change was weak, positive and insignificant. The relationship between Intradialytic HTN and blood flow was weak, negative and insignificant. Conclusion: Intradialytic hypertension is the most important hemodialysis difficulty observed in our country with a higher risk found in subjects with higher weight gain and higher ultrafiltration attentiveness.
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