{"title":"11. 癌症的免疫-致癌物理论——免疫系统与致癌物驱动癌变之间的终身动态界面","authors":"E. Lund","doi":"10.18261/9788215041193-2020-11","DOIUrl":null,"url":null,"abstract":"Over the decades, many theories or models of carcinogenesis have been proposed. Based on the systems epidemiology research on gene expression from immune cells in peripheral blood, the concept of the dynamic interface between the immune system and the carcinogen driven carcinogenesis is put forward. This com-bines traditional exposure research in cancer epidemiology with upcoming knowledge of the immunological response to cancer, from clones of cancer cells to clones of immune cells.","PeriodicalId":386489,"journal":{"name":"Advancing Systems Epidemiology in Cancer","volume":"24 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"11. The Immuno-Carcinogen Theory of Cancer—TheLifelong Dynamic Interface Between the Immune System and the Carcinogen-Driven Carcinogenesis\",\"authors\":\"E. Lund\",\"doi\":\"10.18261/9788215041193-2020-11\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Over the decades, many theories or models of carcinogenesis have been proposed. Based on the systems epidemiology research on gene expression from immune cells in peripheral blood, the concept of the dynamic interface between the immune system and the carcinogen driven carcinogenesis is put forward. This com-bines traditional exposure research in cancer epidemiology with upcoming knowledge of the immunological response to cancer, from clones of cancer cells to clones of immune cells.\",\"PeriodicalId\":386489,\"journal\":{\"name\":\"Advancing Systems Epidemiology in Cancer\",\"volume\":\"24 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-12-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advancing Systems Epidemiology in Cancer\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18261/9788215041193-2020-11\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advancing Systems Epidemiology in Cancer","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18261/9788215041193-2020-11","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
11. The Immuno-Carcinogen Theory of Cancer—TheLifelong Dynamic Interface Between the Immune System and the Carcinogen-Driven Carcinogenesis
Over the decades, many theories or models of carcinogenesis have been proposed. Based on the systems epidemiology research on gene expression from immune cells in peripheral blood, the concept of the dynamic interface between the immune system and the carcinogen driven carcinogenesis is put forward. This com-bines traditional exposure research in cancer epidemiology with upcoming knowledge of the immunological response to cancer, from clones of cancer cells to clones of immune cells.
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