Xiaoying Li, T.G. Constandinoir, A. Eftekhar, P. Georgiou, C. Toumazoi
{"title":"一种用于植入式假肢的仿生神经链","authors":"Xiaoying Li, T.G. Constandinoir, A. Eftekhar, P. Georgiou, C. Toumazoi","doi":"10.1109/CNE.2007.369618","DOIUrl":null,"url":null,"abstract":"This paper presents a biologically-inspired 'silicon neural link', encompassing a neurochemical sensor array, an asynchronous artificial-neural bus and an interleaved biphasic stimulus generator. The proposed system is intended for neuroprosthetic application; employing an array of ISFET-based spiking neurons to convey measured neuronal data across a damaged neural pathway to a target stimulation site. A 48 dB dynamic range is achieved by encoding the neural signal in the time-domain, using accumulating address-events to modulate the biphasic waveform. The electrical stimulation is delivered via a bipolar electrode configuration in a continuous interleave sampling strategy. This has been implemented in a commercially available 035mum CMOS technology.","PeriodicalId":427054,"journal":{"name":"2007 3rd International IEEE/EMBS Conference on Neural Engineering","volume":"44 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2007-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Towards a Bionic Neural Link for Implantable Prosthetics\",\"authors\":\"Xiaoying Li, T.G. Constandinoir, A. Eftekhar, P. Georgiou, C. Toumazoi\",\"doi\":\"10.1109/CNE.2007.369618\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This paper presents a biologically-inspired 'silicon neural link', encompassing a neurochemical sensor array, an asynchronous artificial-neural bus and an interleaved biphasic stimulus generator. The proposed system is intended for neuroprosthetic application; employing an array of ISFET-based spiking neurons to convey measured neuronal data across a damaged neural pathway to a target stimulation site. A 48 dB dynamic range is achieved by encoding the neural signal in the time-domain, using accumulating address-events to modulate the biphasic waveform. The electrical stimulation is delivered via a bipolar electrode configuration in a continuous interleave sampling strategy. This has been implemented in a commercially available 035mum CMOS technology.\",\"PeriodicalId\":427054,\"journal\":{\"name\":\"2007 3rd International IEEE/EMBS Conference on Neural Engineering\",\"volume\":\"44 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-05-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2007 3rd International IEEE/EMBS Conference on Neural Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/CNE.2007.369618\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2007 3rd International IEEE/EMBS Conference on Neural Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/CNE.2007.369618","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Towards a Bionic Neural Link for Implantable Prosthetics
This paper presents a biologically-inspired 'silicon neural link', encompassing a neurochemical sensor array, an asynchronous artificial-neural bus and an interleaved biphasic stimulus generator. The proposed system is intended for neuroprosthetic application; employing an array of ISFET-based spiking neurons to convey measured neuronal data across a damaged neural pathway to a target stimulation site. A 48 dB dynamic range is achieved by encoding the neural signal in the time-domain, using accumulating address-events to modulate the biphasic waveform. The electrical stimulation is delivered via a bipolar electrode configuration in a continuous interleave sampling strategy. This has been implemented in a commercially available 035mum CMOS technology.