通过破坏p53-MDM2/MDMX相互作用，用一种新的有前途的p53通路小分子激活剂改善结肠癌治疗

Proceedings of 5th International Electronic Conference on Medicinal Chemistry Pub Date : 2019-10-30 DOI:10.3390/ecmc2019-06306

L. Raimundo, L. Saraíva, Margarida Espadinha, J. Soares, Joana B Loureiro, Juliana Calheiros, N. Nazareth, J. Almeida, M. Alves, Maria-Soledade Santos

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引用次数: 0

摘要

1 laqv / REQUIMTE微生物学研究室、生物科学系,港口,码头,大学制药、葡萄牙,两药物研究所(iMed.ULisboa系),制药,里斯本,葡萄牙里斯本大学、显微镜,三部门实验室细胞生物学,生物医学科学研究所的阿贝尔萨拉萨尔& UMIB Multidisciplinary研究,统一在葡萄牙波尔图大学生物医学,港口,

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Improving colon cancer therapy with a new promising small-molecule activator of the p53-pathway through disruption of p53-MDM2/MDMX interactions

1LAQV/REQUIMTE, Laboratório de Microbiologia, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal, 2Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal, and 3Department of Microscopy, Laboratory of Cell Biology, Institute of Biomedical Sciences Abel Salazar & UMIB, Unity for Multidisciplinary Research in Biomedicine, University of Porto, Porto, Portugal

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Proceedings of 5th International Electronic Conference on Medicinal Chemistry

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