{"title":"RNA基因发现中单个RNA结构元件的探索","authors":"N. Erho, K. Wiese","doi":"10.1109/CIBCB.2010.5510328","DOIUrl":null,"url":null,"abstract":"This paper explores the use of RNA structural elements for RNA gene finding. A classification experiment is performed in which several support vector machine models, based on the properties of individual RNA secondary structure elements, are trained and tested, revealing the structural elements which have properties useful for RNA gene finding. The study finds that the external loop and structure elements with classification accuracies of over 84% and the stemloop, hairpin, and tail elements with classification accuracies around 70% are the most likely structural elements to be successfully exploited by future RNA gene finders.","PeriodicalId":340637,"journal":{"name":"2010 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology","volume":"60 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":"{\"title\":\"An exploration of individual RNA structural elements in RNA gene finding\",\"authors\":\"N. Erho, K. Wiese\",\"doi\":\"10.1109/CIBCB.2010.5510328\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This paper explores the use of RNA structural elements for RNA gene finding. A classification experiment is performed in which several support vector machine models, based on the properties of individual RNA secondary structure elements, are trained and tested, revealing the structural elements which have properties useful for RNA gene finding. The study finds that the external loop and structure elements with classification accuracies of over 84% and the stemloop, hairpin, and tail elements with classification accuracies around 70% are the most likely structural elements to be successfully exploited by future RNA gene finders.\",\"PeriodicalId\":340637,\"journal\":{\"name\":\"2010 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology\",\"volume\":\"60 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-05-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2010 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/CIBCB.2010.5510328\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2010 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/CIBCB.2010.5510328","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
An exploration of individual RNA structural elements in RNA gene finding
This paper explores the use of RNA structural elements for RNA gene finding. A classification experiment is performed in which several support vector machine models, based on the properties of individual RNA secondary structure elements, are trained and tested, revealing the structural elements which have properties useful for RNA gene finding. The study finds that the external loop and structure elements with classification accuracies of over 84% and the stemloop, hairpin, and tail elements with classification accuracies around 70% are the most likely structural elements to be successfully exploited by future RNA gene finders.