RNA基因发现中单个RNA结构元件的探索

N. Erho, K. Wiese
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引用次数: 5

摘要

本文探讨了RNA结构元件在RNA基因发现中的应用。在分类实验中,基于单个RNA二级结构元件的特性,对多个支持向量机模型进行了训练和测试,揭示了具有对RNA基因发现有用特性的结构元件。研究发现,分类精度在84%以上的外环和结构元件以及分类精度在70%左右的茎环、发簪和尾部元件是未来RNA基因发现者最有可能成功利用的结构元件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An exploration of individual RNA structural elements in RNA gene finding
This paper explores the use of RNA structural elements for RNA gene finding. A classification experiment is performed in which several support vector machine models, based on the properties of individual RNA secondary structure elements, are trained and tested, revealing the structural elements which have properties useful for RNA gene finding. The study finds that the external loop and structure elements with classification accuracies of over 84% and the stemloop, hairpin, and tail elements with classification accuracies around 70% are the most likely structural elements to be successfully exploited by future RNA gene finders.
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