应用ecog -功能状态量表评价宫颈癌患者的生活质量

Shubham Lingappanoor, Geetha Rani Manupati, V. Meesala, Padma Yaragani, Brahmani Bachu, S. Anchuri
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引用次数: 1

摘要

背景:宫颈癌正在成为妇女新出现的健康负担之一,印度占全球宫颈癌死亡人数的三分之一。超过80%患有子宫颈癌的妇女是在晚期被诊断出来的。本研究旨在评估宫颈癌患者治疗后的生活质量(QOL),并探讨影响其生活质量的因素。材料与方法:本研究为回顾性观察性研究,纳入218例宫颈癌患者。这项研究是在特伦加纳邦瓦朗加尔的一家三级保健医院进行的。采用东方肿瘤合作小组绩效状况量表(ECOG-PS)研究社会经济因素和临床因素对患者生活质量的影响。该协议由瓦朗加尔KIEC-KMC批准。统计分析采用Fischer’s Exact检验,p<。0.05为显著性。结果:218例患者中存活189例,死亡29例。年龄21 ~ 40岁、城市地区、社会经济地位较高、文化程度高、无社会生活习惯的患者生活质量较好,而劳动力地区患者生活质量较差,差异有统计学意义。早期诊断和手术加放化疗患者的生活质量较好,但差异无统计学意义。结论:由于保健部门缺乏获得预防性和决定性护理的机会,加上妇女的社会经济地位、教育状况和对疾病及其治疗模式的认识较差,导致随访不良,治疗依从性低,从而加重了宫颈癌的负担。因此,提高上述因素对改善宫颈癌患者的生活质量是有益的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of Quality of Life of Cervical Cancer Patients Using ECOG-Performance Status Scale
Background: Cervical cancer is becoming one of the emerging health burdens for womenhood and India accounts for one-third of the cervical cancer deaths globally. More than 80% of women with cervical cancer are diagnosed at an advanced stage. In this study, we aimed to assess the Quality of Life (QOL) of patients with cervical cancer after treatment and to examine the factors affecting their QOL. Materials and Methods: This is a retrospective observational study, included 218 cervical cancer patients. The study was conducted in a tertiary care hospital in Warangal of Telangana State. The impact of socioeconomic factors and clinical factors on the QOL of the patients were studied using Eastern Cooperative Oncology Group-Performance status (ECOG-PS) scale. The protocol was approved by KIEC-KMC, Warangal. The statistical analysis was performed by using Fischer's Exact test, a value of p<.05 was considered as significant. Results: Out of 218 patients 189 were alive and 29 were deceased. Patient of age group 21-40 years, patients from urban areas, from upper socioeconomic status (SES), patients with literacy, without any social habits had good QOL, where as patients in labour forces had poor QOL and are statistically significant. Patients with early stage at diagnosis and patients underwent surgical treatment along with chemoradiation therapy had good QOL yet, these results are statistically insignificant. Conclusion: The lack of access to preventive and definitive care by the health care sectors, poor socioeconomic status, educational status of the women and awareness regarding the disease and its treatment patterns resulted in poor follow up, low adherence to the treatment, which accentuated the cervical cancer burden. Hence, enhancing the above listed factors could be beneficial in improving QOL of cervical cancer patients.
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