{"title":"基于rSPR局部搜索的快速基因复制算法","authors":"Jian Zhang, Daming Zhu","doi":"10.1109/ICACTE.2010.5579138","DOIUrl":null,"url":null,"abstract":"The gene-duplication problem is to infer a species tree from a collection of gene trees. As we know, this problem is NP-hard and thus requires efficient heuristics. Existing heuristics for this problem performs a stepwise search of the tree space which consists of all potential species trees. Each step in heuristics is guided by an exact solution to an instance of local search problem. The local search problem is to find an optimal species tree in the tree space. Computing the mapping for gene trees and a species tree is a necessary step in the local search problem. In this paper, we give an improved algorithm to determine the mapping between gene trees and a species tree in the gene-duplication problem based on the rooted subtree pruning and regrafting (rSPR) operation. This algorithm eliminates some redundant calculations and is faster than former algorithms.","PeriodicalId":255806,"journal":{"name":"2010 3rd International Conference on Advanced Computer Theory and Engineering(ICACTE)","volume":"65 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A faster algorithm for gene-duplication problem based on rSPR local search\",\"authors\":\"Jian Zhang, Daming Zhu\",\"doi\":\"10.1109/ICACTE.2010.5579138\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The gene-duplication problem is to infer a species tree from a collection of gene trees. As we know, this problem is NP-hard and thus requires efficient heuristics. Existing heuristics for this problem performs a stepwise search of the tree space which consists of all potential species trees. Each step in heuristics is guided by an exact solution to an instance of local search problem. The local search problem is to find an optimal species tree in the tree space. Computing the mapping for gene trees and a species tree is a necessary step in the local search problem. In this paper, we give an improved algorithm to determine the mapping between gene trees and a species tree in the gene-duplication problem based on the rooted subtree pruning and regrafting (rSPR) operation. This algorithm eliminates some redundant calculations and is faster than former algorithms.\",\"PeriodicalId\":255806,\"journal\":{\"name\":\"2010 3rd International Conference on Advanced Computer Theory and Engineering(ICACTE)\",\"volume\":\"65 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-09-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2010 3rd International Conference on Advanced Computer Theory and Engineering(ICACTE)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICACTE.2010.5579138\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2010 3rd International Conference on Advanced Computer Theory and Engineering(ICACTE)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICACTE.2010.5579138","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A faster algorithm for gene-duplication problem based on rSPR local search
The gene-duplication problem is to infer a species tree from a collection of gene trees. As we know, this problem is NP-hard and thus requires efficient heuristics. Existing heuristics for this problem performs a stepwise search of the tree space which consists of all potential species trees. Each step in heuristics is guided by an exact solution to an instance of local search problem. The local search problem is to find an optimal species tree in the tree space. Computing the mapping for gene trees and a species tree is a necessary step in the local search problem. In this paper, we give an improved algorithm to determine the mapping between gene trees and a species tree in the gene-duplication problem based on the rooted subtree pruning and regrafting (rSPR) operation. This algorithm eliminates some redundant calculations and is faster than former algorithms.