腹膜前骨盆填充物联合外固定器与单独骨盆填充物治疗骨盆骨折血流动力学不稳定患者历史队列研究

H. Khoshmohabat, Shahram Paydar, M. A. Agah
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摘要

背景:骨盆骨折是创伤患者最常见的死亡原因之一。本研究旨在比较外伤性骨盆骨折和血流动力学不稳定患者采用腹膜前盆腔填充物联合外固定器与单独盆腔填充物治疗的结果、发病率和并发症。方法采用回顾性病例对照研究方法,对2018年8月至2019年8月在急诊科和外科就诊的骨盆骨折伴血流动力学不稳定患者进行调查。在对照组中,25例患者仅接受腹膜前包装(PPP组),而在病例组中,22例患者接受腹膜前包装和外固定架作为控制出血的程序(PPP +固定架组)。比较两组患者的血栓栓塞、住院时间、感染、BUN、肌酐、输血率和死亡率。结果盆腔包组平均年龄为34.48±13.79岁,PPP +外固定架组平均年龄为32.36±16.29岁。骨盆包组损伤严重程度评分(ISS)平均为23.12±9.85,PPP +外固定架组平均为19.22±8.09。PPP组急性肾损伤6例(24%),PPP +固定器组急性肾损伤发生率40.9%。对照组和病例组的死亡率分别为32%和4.5%。两组间差异有统计学意义(p=0.017, LR=6.42)。PPP组和PPP +固定器组VTE分别为12%和4.5%。结论PPP外固定架是治疗骨盆骨折血流动力学不稳定的一种有效方法。建议使用乳酸盐或其他生物标志物尽可能准确地确定患者的情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pre-peritoneal Pelvic Pack with External Fixator versus Pelvic Pack Alone for Hemodynamically Unstable Patients with Pelvic Fracture; a Historical Cohort Study
BackgroundPelvic fracture is one of the most common cause of death in traumatic patients. This study was designed to compare the outcome, morbidity and complications of treatment with pre-peritoneal pelvic pack with external fixator against pelvic pack alone in traumatic pelvic fracture and unstable hemodynamic patients.MethodsIn a retrospective case control study, patients with pelvic fracture and unstable hemodynamic state who referred to emergency and surgery department from August 2018 to August 2019 were enrolled by census manner. In the control group, 25 patients treated just by a pre-peritoneal pack (PPP group), while in the case group, pre-peritoneal pack and external fixator was done as the procedure to control bleeding (PPP Plus fixator group) in 22 individuals. Two groups were compared for presence of thromboembolism, hospital stay, infection, BUN, creatinine, rate of blood transfusion and mortality. ResultsMean age of participants were 34.48 ± 13.79 in pelvic pack group, while it was 32.36±16.29 in PPP plus external fixator ones. The mean Injury Severity Score (ISS) was 23.12±9.85 in Pelvic Pack group, and 19.22±8.09 in PPP plus external fixator group. Acute kidney injury was reported in 6 (24%) individuals of PPP group, while its rate in PPP plus fixator group was 40.9%. Mortality rate was reported 32% and 4.5% in control and case groups, respectively. There was a significant difference between groups (p=0.017, LR=6.42). VTE was reported 12% and 4.5% in PPP group and PPP plus fixator ones, respectively.ConclusionIt was concluded that using external fixator with PPP can be a useful method for treatment of pelvic fracture that is unstable in hemodynamic situation. It is recommended to use biomarkers like lactate or others to determine the situation of patients as precise as possible.
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