{"title":"为什么伦巴第省COVID-19死亡率如此之高?SEIHCR模式模拟的证据","authors":"Carlo A. Favero","doi":"10.2139/ssrn.3566865","DOIUrl":null,"url":null,"abstract":"The standard SEIR model based on a parameterization consistent with the international evidence cannot explain the very high COVID-19 related mortality in Lombardy. This paper proposes an extension of the standard SEIR model that is capable of solving the puzzle. The SEIR model features exogenous mortality: once Susceptible individuals become first Exposed, and then Infected, they succumb with a given probability. The extended model inlcudes an Hospitlization process and the possibility that Hospitalized patients, who need to resort to Intensive Care Unit, cannot find availability because the ICU is saturated. This Constraint creates an additional increase in mortality, which is endogenous to the diffusion of the disease. The SEIHCR (H stands for Hospitalization and C stands for Constraint) is capable of explaining the dynamics of COVID-19 related mortality in Lombardy with a paramerization consistent with the international evidence.","PeriodicalId":132014,"journal":{"name":"MedRN: Respiratory Tract Infections (Topic)","volume":"45 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"18","resultStr":"{\"title\":\"Why Is COVID-19 Mortality in Lombardy so High? Evidence from the Simulation of a SEIHCR Model\",\"authors\":\"Carlo A. Favero\",\"doi\":\"10.2139/ssrn.3566865\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The standard SEIR model based on a parameterization consistent with the international evidence cannot explain the very high COVID-19 related mortality in Lombardy. This paper proposes an extension of the standard SEIR model that is capable of solving the puzzle. The SEIR model features exogenous mortality: once Susceptible individuals become first Exposed, and then Infected, they succumb with a given probability. The extended model inlcudes an Hospitlization process and the possibility that Hospitalized patients, who need to resort to Intensive Care Unit, cannot find availability because the ICU is saturated. This Constraint creates an additional increase in mortality, which is endogenous to the diffusion of the disease. The SEIHCR (H stands for Hospitalization and C stands for Constraint) is capable of explaining the dynamics of COVID-19 related mortality in Lombardy with a paramerization consistent with the international evidence.\",\"PeriodicalId\":132014,\"journal\":{\"name\":\"MedRN: Respiratory Tract Infections (Topic)\",\"volume\":\"45 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-04-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"18\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"MedRN: Respiratory Tract Infections (Topic)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2139/ssrn.3566865\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"MedRN: Respiratory Tract Infections (Topic)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2139/ssrn.3566865","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Why Is COVID-19 Mortality in Lombardy so High? Evidence from the Simulation of a SEIHCR Model
The standard SEIR model based on a parameterization consistent with the international evidence cannot explain the very high COVID-19 related mortality in Lombardy. This paper proposes an extension of the standard SEIR model that is capable of solving the puzzle. The SEIR model features exogenous mortality: once Susceptible individuals become first Exposed, and then Infected, they succumb with a given probability. The extended model inlcudes an Hospitlization process and the possibility that Hospitalized patients, who need to resort to Intensive Care Unit, cannot find availability because the ICU is saturated. This Constraint creates an additional increase in mortality, which is endogenous to the diffusion of the disease. The SEIHCR (H stands for Hospitalization and C stands for Constraint) is capable of explaining the dynamics of COVID-19 related mortality in Lombardy with a paramerization consistent with the international evidence.