{"title":"1,25-二羟基胆骨化醇对小鼠颅骨3′，5′-环单磷酸腺苷生成的影响。","authors":"U Gebauer, H Fleisch","doi":"10.1007/BF02010773","DOIUrl":null,"url":null,"abstract":"<p><p>1,25-dihydroxycholecalciferol (1,25-(OH)2D3), added at doses which stimulate bone resorption in the system used, did not increase adenosine 3',5'-cyclic monophosphate (cAMP) production in vitro in mouse calvaria incubated for up to 48 h. Thus 1,25-(OH)2D3 does not appear to stimulate bone resorption through involvement of an increased cAMP production.</p>","PeriodicalId":9389,"journal":{"name":"Calcified Tissue Research","volume":"25 3","pages":"223-5"},"PeriodicalIF":0.0000,"publicationDate":"1978-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02010773","citationCount":"3","resultStr":"{\"title\":\"Effect of 1,25-dihydroxycholecalciferol on adenosine 3',5'-cyclic monophosphate production in calvaria of mice.\",\"authors\":\"U Gebauer, H Fleisch\",\"doi\":\"10.1007/BF02010773\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>1,25-dihydroxycholecalciferol (1,25-(OH)2D3), added at doses which stimulate bone resorption in the system used, did not increase adenosine 3',5'-cyclic monophosphate (cAMP) production in vitro in mouse calvaria incubated for up to 48 h. Thus 1,25-(OH)2D3 does not appear to stimulate bone resorption through involvement of an increased cAMP production.</p>\",\"PeriodicalId\":9389,\"journal\":{\"name\":\"Calcified Tissue Research\",\"volume\":\"25 3\",\"pages\":\"223-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1978-08-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1007/BF02010773\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Calcified Tissue Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/BF02010773\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Calcified Tissue Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/BF02010773","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effect of 1,25-dihydroxycholecalciferol on adenosine 3',5'-cyclic monophosphate production in calvaria of mice.
1,25-dihydroxycholecalciferol (1,25-(OH)2D3), added at doses which stimulate bone resorption in the system used, did not increase adenosine 3',5'-cyclic monophosphate (cAMP) production in vitro in mouse calvaria incubated for up to 48 h. Thus 1,25-(OH)2D3 does not appear to stimulate bone resorption through involvement of an increased cAMP production.
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