低成本快速定量血液中生物标志物的硅光子学系统

2023 IEEE Silicon Photonics Conference (SiPhotonics) Pub Date : 2023-04-01 DOI:10.1109/SiPhotonics55903.2023.10141929

Ebrahim Aljohani, S. Gundavarapu, Cole A. Chapman, Armando Paredes Arroyo, Guojun Chen, Chi-Chen Lin, Andrea Romig, Kyle Preston, Alexander Vinitsky, Alana Gonzales, Eric Hsu, Jordan Cobb, Yulia Rybakova, M. Dubrovsky, D. Vermeulen

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引用次数: 0

摘要

我们介绍了一种低成本的扫描源光学读取器和一次性微流体盒系统，用于多路护理点和使用光子微谐振器的家庭诊断。在一项血浆中高灵敏度c反应蛋白(hsCRP)定量的三盲研究中，我们的系统与金标准实验室测量技术表现出良好的一致性(R>0.9)。

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Silicon Photonics System for Low-Cost Rapid Quantification of Biomarkers in Blood

We introduce a low-cost swept-source optical reader and disposable microfluidic cartridge system for multiplexed point-of-care and at-home diagnostics using photonic microresonators. In a triple-blind study of high-sensitivity C-Reactive Protein (hsCRP) quantification in blood plasma, our system demonstrated good agreement (R>0.9) with gold-standard lab measurement techniques.

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2023 IEEE Silicon Photonics Conference (SiPhotonics)

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