传染性猴泡沫病毒DNA在持续感染中的可能作用。

C T Chu, J J Hooks
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引用次数: 0

摘要

猴7型泡沫病毒(SFV-7)可在SFV-7感染家兔的外周血白细胞中持续存在。体外培养的兔外周血白细胞不支持SFV-7的生长,但培养4 ~ 5天后可检测到低滴度病毒。从SFV-7感染的原代兔肾细胞中提取的DNA具有传染性。感染的兔肾细胞在复制过程中存在SFV-7 DNA前病毒可能是其持续存在的机制之一。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Possible role of infectious simian foamy virus DNA in persistent infection.

Simian foamy virus type 7 (SFV-7) can persist in peripheral blood leukocytes of SFV-7-infected rabbits. Rabbit peripheral blood leukoyctes cultured in vitro did not support the growth of SFV-7, but low titer of virus could be detected after 4 to 5 days incubation. The DNA derived from SFV-7 infected primary rabbit kidney cells is infectious. The presence of SFV-7 DNA provirus in infected rabbit kidney cells during replication may contribute one of the mechanisms of persistance.

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