心脏瓣膜叶运动的定点及稳定性分析

E. Emagbetere, T. Salau, O. Oluwole
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引用次数: 0

摘要

这项工作是为了进一步深入了解人类心脏瓣膜叶的动力学。本研究采用Korakianitis和Shi的集总参数模型。确定不动点,然后通过计算雅可比矩阵的特征值来评价不动点的稳定性。模拟瓣膜模型的正常生理参数;在此基础上,生成了局部分支图。从模拟响应中绘制相图,并用于观察阀叶运动的定性特性。所评估的固定点取决于压力和流量效应,而与摩擦或阻尼效应无关。观察到两个不动点之间的稳定性切换表明,小叶运动经历了跨临界分叉。在两个不动点中,一个总是稳定的螺旋节点或生成节点,而另一个总是鞍节点。数值模拟验证了解析解的正确性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fixed Points and Stability Analysis in the Motion of Human Heart Valve Leaflet
This work was set out to gain further insight into the kinetics of the human heart valve leaflet. The Korakianitis and Shi lumped parameter model was adopted for this study. The fixed points were determined, and then, their stability properties were assessed by evaluating eigenvalues of the Jacobian matrices. Normal physiological parameters for the valve model were simulated; based on which, a local bifurcation diagram was generated. Phase portraits were plotted from simulated responses, and were used to observe the qualitative properties of the valve leaflet motion. The evaluated fixed points were found to be dependent on pressure and flow effects, and independent on friction or damping effect. Observed switching of stability between the two fixed points indicated that the leaflet motion undergoes transcritical bifurcation. Of the two fixed points, one is always either a stable spiral or generative node while the other is a saddle. Numerical simulations were carried out to verify the analytical solutions.
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