Opioid-Free Naloxone Emergence Under Dexmedetomidine: A Case Report

This report describes a case in which naloxone appeared to expedite emergence from general anesthesia in a patient who underwent an opioid-free anesthetic that included dexmedetomidine. After administration of naloxone, the patient progressed rapidly from general anesthesia to alert and oriented in approximately two minutes. Additionally, the patient demonstrated rapid reversal of miosis. He also reported adequate analgesia in the PACU, requiring no opioids and denied any recall of events that occurred prior to the administration of naloxone. Keywords: Naloxone, Dexmedetomidine, Delayed emergence.