一些抗胆酸药物的代谢作用:胆酸对大鼠肝脏中nad1连接底物氧化的抑制作用。

Egyptian journal of bilharziasis Pub Date : 1978-01-01
A A Sharaf, A el-Sherbini, W A Abdulla
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引用次数: 0

摘要

BILHARCID抑制苹果酸和丙酮酸的氧化。当Bilharcid浓度为10(-3)m时,抑制程度达到50%。参考腺嘌呤和吡啶核苷酸对氧化还原酶活性的影响,讨论了该药抑制作用的机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Metabolic effects of some antibilharzial drugs: inhibition of NAD-linked substrate oxidation in rat liver by bilharcid.

BILHARCID inhibited malate and pyruvate oxidation. The degree of inhibition reached 50% when the concentration of Bilharcid was 10(-3) M. The mechanisms of the inhibitory action of the drug are discussed with reference to the effects of both adenine and pyridine nucleotides on the activity of the oxidoreductase enzymes.

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