【马来酸过hexilline引起的水肿性视神经病变与周围多神经病变相关(作者译)】。

Archives d'ophtalmologie Pub Date : 1977-01-01

R van Effenterre, M Poisson, G van Effenterre, M Schaison, J P Sichez, J Haut

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引用次数: 0

摘要

作者报告了一例与长期使用马来酸过己林(一种自1973年起在法国用于治疗冠状动脉功能不全的药物)治疗相关的多根神经病变，其表现为双侧水肿性视神经病变。讨论了这种作用对视神经和乳头状水肿的作用机制;这似乎不是由直接毒性作用引起的，而是由慢性颅内高压的存在引起的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Oedematous optic neuropathy from Perhexilline maleate associated with peripheral polyneuropathy (author's transl)].

The authors report on a polyradiculoneuropathy related to long-term treatment with Perhexiline maleate (a drug used in France since 1973 for coronary insufficiency) whose presenting sign is a bilateral aedematous optic neuropathy. The mechanism of this effect on the optic nerves and on papilloedema is discussed; it seems not to be caused by a direct toxic action on the optic fibres but by the existence of chronic intracranial hypertension.

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来源期刊

Archives d'ophtalmologie

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