扩散纳米粒子和人工电流产生排斥效应

H. Nieto-Chaupis
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引用次数: 0

摘要

纳米医学迫在眉睫的进步清楚地反映在基于药物输送到被异常组织和肿瘤污染的具体部位的技术的实施上。众所周知的纳米粒子是一种很有前途的强大载体。因此,人们期望工程纳米颗粒在完成超越当前药理学方面已知成就的确切任务方面发挥关键作用。然而,在所有这些表面带电的纳米粒子中,人们可以预期其潜在的功能,这可能是靶向药物输送计划和医疗目的的主要作用的缺点。本文提出了一种理论,认为纳米电流的出现会导致纳米粒子的持续积聚,而这种积聚是由扩散效应引起的,并确定了由此产生的后果。由此导出了扩散系数的显式依赖关系。这将在需要精确和效率的高级肿瘤学中获得相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diffusive Nanoparticles and Generation of Repulsive Effects by Artificial Electrical Currents
The imminent advance of Nanomedicine is clearly reflected in the implementation of techniques based on drug deliv-ery towards concrete places that are contaminated by anomalous tissues and tumors. A promising as well as robust vehicle are the well- known nanoparticle. Therefore one expects a crucial role of engineered nanoparticles to accomplish exact tasks surpassing known achievements from the side of current pharmacology. However, in all those charged superficially nanoparticles one can expect a latent function that might be a disadvantage as to the main role of targeted drug delivery schemes and medical purposes. In this paper, a theory the apparition of nanocurrents produced a continue accumulation of charged nanoparticles, and that would be caused by diffusive effects is constructed and the consequences from it are identified. Thus, from the results of this paper the explicit dependence of diffusion coefficient is derived. This would acquire relevance in the advanced Oncology that requires of precision and efficiency.
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