在两个独立的严重哮喘队列中，与未解决的炎症和气道重塑相关的途径是转录组的特征

Respirology (Carlton, Vic.) Pub Date : 2022-06-07 DOI:10.1111/resp.14302

S. Sánchez-Ovando, S. Pavlidis, N. Kermani, K. Baines, D. Barker, P. Gibson, L. Wood, I. Adcock, K. Chung, J. Simpson, P. Wark

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引用次数: 2

摘要

严重哮喘(SA)是一种异质性疾病。转录组学分析有助于了解发病机制，开发新的治疗方法。我们试图在两个独立的队列中识别和验证SA的机制途径。

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Pathways linked to unresolved inflammation and airway remodelling characterize the transcriptome in two independent severe asthma cohorts

Severe asthma (SA) is a heterogeneous disease. Transcriptomic analysis contributes to the understanding of pathogenesis necessary for developing new therapies. We sought to identify and validate mechanistic pathways of SA across two independent cohorts.

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Respirology (Carlton, Vic.)

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