最近建立的两种人类肿瘤细胞系的染色体分析,这些细胞系来源于食道癌和原发性肝癌。

K Robinson, E Bey, J J Alexander, J H Gear
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引用次数: 0

摘要

对食管癌细胞系进行了8、48、64、88代核型分析。结果显示,D组染色体持续缺失,常出现亚远心、远心、双心等标记。在80个航段中,模态数从60,5下降到54,09。对肝癌细胞系的染色体模式进行了第15/17和28代的研究。结果显示D组和G组染色体缺失,存在包括D/G融合在内的各种标记。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Chromosome analyses of two recently established human tumour cell lines derived from a carcinoma of the oesophagus and a primary liver tumour.

An oesophageal carcinoma cell line was karyotyped at passages 8,48,64 and 88. It showed a persistent loss of D group chromosomes and subtelocentric, acrocentric, dicentric and other markers were frequently present. During 80 passages the modal number declined from 60,5 to 54,09. The chromosome pattern of a hepatoma cell line was studied at passages 15/17 and 28. It showed a loss of D and G group chromosomes and the presence of various markers including a D/G fusion.

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