Rafaela Ortega Castro, Alejandro Escudero Contreras, Jerusalén Calvo Gutiérrez, Maria del Carmen Castro Villegas, Eduardo Collantes Estévez
{"title":"甲氨蝶呤的最佳使用","authors":"Rafaela Ortega Castro, Alejandro Escudero Contreras, Jerusalén Calvo Gutiérrez, Maria del Carmen Castro Villegas, Eduardo Collantes Estévez","doi":"10.1016/j.semreu.2013.01.004","DOIUrl":null,"url":null,"abstract":"<div><p>Methotrexate is considered today as the modifying antirheumatic drugs of first choice in the treatment of rheumatoid arthritis, due to its effectiveness in delaying the anatomical damage, low cost, safety and long therapeutic segment. For optimal use we must consider its pharmacological properties, the dosage, route of administration and the administration with folate, among other items, we will see in more detail below.</p></div>","PeriodicalId":101152,"journal":{"name":"Seminarios de la Fundación Espa?ola de Reumatología","volume":"14 1","pages":"Pages 24-27"},"PeriodicalIF":0.0000,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.semreu.2013.01.004","citationCount":"1","resultStr":"{\"title\":\"Óptima utilización del metotrexato\",\"authors\":\"Rafaela Ortega Castro, Alejandro Escudero Contreras, Jerusalén Calvo Gutiérrez, Maria del Carmen Castro Villegas, Eduardo Collantes Estévez\",\"doi\":\"10.1016/j.semreu.2013.01.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Methotrexate is considered today as the modifying antirheumatic drugs of first choice in the treatment of rheumatoid arthritis, due to its effectiveness in delaying the anatomical damage, low cost, safety and long therapeutic segment. For optimal use we must consider its pharmacological properties, the dosage, route of administration and the administration with folate, among other items, we will see in more detail below.</p></div>\",\"PeriodicalId\":101152,\"journal\":{\"name\":\"Seminarios de la Fundación Espa?ola de Reumatología\",\"volume\":\"14 1\",\"pages\":\"Pages 24-27\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.semreu.2013.01.004\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Seminarios de la Fundación Espa?ola de Reumatología\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1577356613000055\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminarios de la Fundación Espa?ola de Reumatología","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1577356613000055","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Methotrexate is considered today as the modifying antirheumatic drugs of first choice in the treatment of rheumatoid arthritis, due to its effectiveness in delaying the anatomical damage, low cost, safety and long therapeutic segment. For optimal use we must consider its pharmacological properties, the dosage, route of administration and the administration with folate, among other items, we will see in more detail below.
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