细胞神经网络,Navier-Stokes方程和微阵列图像重建

B. Zineddin, Zidong Wang, Xiaohui Liu
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引用次数: 1

摘要

尽管微阵列技术有了最新的改进,但在图像处理阶段还需要许多发展。已经提出了一些微阵列图像处理的硬件实现,并被证明是目前可用的软件系统的一个有前途的替代方案。然而,该方法的主要缺点是对基因斑点的定量处理不合适,这依赖于许多假设。本文的目的是提出一种新的基于细胞神经网络的图像重建算法,该算法求解了Navier-Stokes方程。该算法为基因斑点区域内的背景信号估计提供了一种鲁棒的方法。从客观立场出发,将我们的方法与现有的一些方法进行了定量比较。结果表明,该算法能以完全自动化的方式,在相当短的时间内,给出高度精确和真实的测量结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cellular Neural Networks, Navier-Stokes equation and microarray image reconstruction
Despite the latest improvements in the microarray technology, many developments are needed particularly in the image processing stage. Some hardware implementations of microarray image processing have been proposed and proved to be a promising alternative to the currently available software systems. However, the main drawback is the unsuitable addressing of the quantification of the gene spots which depend on many assumptions. It is our aim in this paper to present a new Image Reconstruction algorithm using Cellular Neural Network, which solves the Navier-Stokes equation. This algorithm offers a robust method to estimate the background signal within the gene spot region. Quantitative comparisons are carried out, between our approach and some available methods in terms of objective standpoint. It is shown that the proposed algorithm gives highly accurate and realistic measurements in a fully automated manner, and also, in a remarkably efficient time.
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