{"title":"乙型肝炎病毒感染模型与logistic肝细胞生长和细胞毒性t淋巴细胞反应的动力学","authors":"K. Allali, Adil Meskaf, Y. Tabit","doi":"10.12988/NADE.2016.510642","DOIUrl":null,"url":null,"abstract":"Abstract In this paper, we present and study the mathematical model of HBV dynamics with logistic hepatocyte growth and cytotoxic T-lymphocyte (CTL) response. The positivity and boundedness of solutions for nonnegative initial data are proved. The stability of disease-free equilibrium and endemic equilibrium are analyzed. Numerical simulations are performed and oscillatory convergence is observed.","PeriodicalId":315586,"journal":{"name":"Nonlinear Analysis and Differential Equations","volume":"53 S3","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Dynamics of a hepatitis B viral infection model with logistic hepatocyte growth and cytotoxic T-lymphocyte response\",\"authors\":\"K. Allali, Adil Meskaf, Y. Tabit\",\"doi\":\"10.12988/NADE.2016.510642\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract In this paper, we present and study the mathematical model of HBV dynamics with logistic hepatocyte growth and cytotoxic T-lymphocyte (CTL) response. The positivity and boundedness of solutions for nonnegative initial data are proved. The stability of disease-free equilibrium and endemic equilibrium are analyzed. Numerical simulations are performed and oscillatory convergence is observed.\",\"PeriodicalId\":315586,\"journal\":{\"name\":\"Nonlinear Analysis and Differential Equations\",\"volume\":\"53 S3\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nonlinear Analysis and Differential Equations\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.12988/NADE.2016.510642\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nonlinear Analysis and Differential Equations","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12988/NADE.2016.510642","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Dynamics of a hepatitis B viral infection model with logistic hepatocyte growth and cytotoxic T-lymphocyte response
Abstract In this paper, we present and study the mathematical model of HBV dynamics with logistic hepatocyte growth and cytotoxic T-lymphocyte (CTL) response. The positivity and boundedness of solutions for nonnegative initial data are proved. The stability of disease-free equilibrium and endemic equilibrium are analyzed. Numerical simulations are performed and oscillatory convergence is observed.