增强检测细胞路径在时空图的非侵入性显微镜的人视网膜

Johnny Tam, A. Roorda
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引用次数: 8

摘要

时空(ST)图已被用于研究微循环中的细胞运动。然而,ST图通常用于侵入性成像方法。人类视网膜毛细血管的无创视频显微镜可以使用自适应光学扫描激光检眼镜进行,但由于低对比度和高噪声,直接实现ST图是困难的。我们引入运动对比度增强来增强细胞路径的检测,并使ST图分析成为可能。利用运动对比度增强生成的特征,提出了一种自动提取细胞路径的方法。我们的研究结果表明,运动对比度是低信噪比视频的ST图分析的重要先导步骤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Enhanced detection of cell paths in spatiotemporal plots for noninvasive microscopy of the human retina
Spatiotemporal (ST) plots have been used for studying cell motion in the microcirculation. However, ST plots are typically applied to invasive imaging methods. Noninvasive video microscopy of the human retinal capillaries can be performed using an Adaptive Optics Scanning Laser Ophthalmoscope, but direct implementation of ST plots is difficult due to low contrast and high noise. We introduce motion contrast enhancement to enhance detection of cell paths, and enable ST plot analysis. Using features generated by the motion contrast enhancement, a method for automatic extraction of cell paths was developed. Our results show that motion contrast is an important precursor step to ST plot analysis for videos with low signal to noise ratios.
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