{"title":"[abo - ii系统中的自身抗体(作者译)]。","authors":"W Graninger","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Nine cases of autoantibodies in the ABO-system, found by routine investigations, showed the following specificities by agglutination, absorption, and elution techniques: 5 anti-AI, 2 anti-(not-I)-A, I anti-BI and 1 anti-HI. Neutralization experiments by blood group substances revealed heterogeneity among the 5 anti-AI-cases. This is interpreted by different antibody specificities directed against I-antigen components. The relations between the ABO- and Ii-systems are discussed. The occurrence of these antibodies is attributed to oligosaccharides, which are common to both antigen systems. The etiology remains unknown.</p>","PeriodicalId":23768,"journal":{"name":"Zeitschrift fur Immunitatsforschung, experimentelle und klinische Immunologie","volume":"150 5","pages":"389-402"},"PeriodicalIF":0.0000,"publicationDate":"1975-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Autoantibodies in the ABO-Ii-system (author's transl)].\",\"authors\":\"W Graninger\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Nine cases of autoantibodies in the ABO-system, found by routine investigations, showed the following specificities by agglutination, absorption, and elution techniques: 5 anti-AI, 2 anti-(not-I)-A, I anti-BI and 1 anti-HI. Neutralization experiments by blood group substances revealed heterogeneity among the 5 anti-AI-cases. This is interpreted by different antibody specificities directed against I-antigen components. The relations between the ABO- and Ii-systems are discussed. The occurrence of these antibodies is attributed to oligosaccharides, which are common to both antigen systems. The etiology remains unknown.</p>\",\"PeriodicalId\":23768,\"journal\":{\"name\":\"Zeitschrift fur Immunitatsforschung, experimentelle und klinische Immunologie\",\"volume\":\"150 5\",\"pages\":\"389-402\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1975-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur Immunitatsforschung, experimentelle und klinische Immunologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Immunitatsforschung, experimentelle und klinische Immunologie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
9例abo系统自身抗体经常规检查，经凝集、吸收和洗脱技术表现出以下特异性:5例抗ai, 2例抗-(非-I)- a, 1例抗bi, 1例抗hi。血型物质中和实验显示5例抗ai患者存在异质性。这是通过针对i抗原成分的不同抗体特异性来解释的。讨论了ABO-和ii -系统之间的关系。这些抗体的发生是由于低聚糖，这是共同的抗原系统。病因尚不清楚。
[Autoantibodies in the ABO-Ii-system (author's transl)].
Nine cases of autoantibodies in the ABO-system, found by routine investigations, showed the following specificities by agglutination, absorption, and elution techniques: 5 anti-AI, 2 anti-(not-I)-A, I anti-BI and 1 anti-HI. Neutralization experiments by blood group substances revealed heterogeneity among the 5 anti-AI-cases. This is interpreted by different antibody specificities directed against I-antigen components. The relations between the ABO- and Ii-systems are discussed. The occurrence of these antibodies is attributed to oligosaccharides, which are common to both antigen systems. The etiology remains unknown.
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