[通过抗β -内啡肽揭示人脑底核神经元中β - lph、β - msh、α -内啡肽、ACTH和α - msh的抗原决定因素]。

Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles Pub Date : 1978-10-30

B Bloch, C Bugnon, D Fellmann, D Lenys

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引用次数: 0

摘要

成人下丘脑结节-基底区相邻连续切片的比较表明，相同的核周、轴突和终末均被抗-内啡肽和抗17-39 ACTH抗血清染色。这些神经元中最具免疫活性的还有抗-内啡肽、抗-和- msh、抗-1-24 ACTH和抗- lph。这些结果表明，漏斗核的神经元可以储存并可能分泌类似丙皮素的肽或该分子的片段。

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[Antigenic determinants of beta-LPH, beta-MSH, alpha-endorphin, ACTH and alpha-MSH revealed by anti-beta-endorphin in neurons of the human infundibular nucleus].

Comparison of adjacent serial sections of the tubero-infundibular region of Human adult hypothalamus demonstrates that the same perikarya, axons and terminals are stained both with anti-beta-endorphin and anti 17-39 ACTH antisera. The most immunoreactive of these neurons are also revealed with anti alpha-endorphin, anti alpha and beta-MSH, anti-1-24 ACTH and anti beta-LPH. These results suggest that neurons of the infundibular nucleus can store and probably secrete peptide similar to propiocortin or fragment(s) of this molecule.

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Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles

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