{"title":"n -甲基Isatin β-硫代氨基脲-铜复合物抑制rna依赖性DNA聚合酶，但不抑制核糖核酸酶rous肉瘤病毒","authors":"Lu-Hai Wang, Warren Levinson","doi":"10.1016/0006-3061(78)80007-6","DOIUrl":null,"url":null,"abstract":"<div><p><em>N</em>-Methyl isatin β-thiosemicarbazone-copper complex inhibits the RNA-dependent DNA polymerase activity of Rous sarcoma virus (RSV), but not its ribonuclease H. activity. In addition, bovine pancreatic RNase and DNase are not inhibited by the complex.</p></div>","PeriodicalId":9177,"journal":{"name":"Bioinorganic chemistry","volume":"8 6","pages":"Pages 535-540"},"PeriodicalIF":0.0000,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0006-3061(78)80007-6","citationCount":"5","resultStr":"{\"title\":\"N-Methyly Isatin β-thiosemicarbazone-Copper Complex Inhibits RNA-Dependent DNA Polymerase but not Ribunuclease rous Sarcoma Virus\",\"authors\":\"Lu-Hai Wang, Warren Levinson\",\"doi\":\"10.1016/0006-3061(78)80007-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><em>N</em>-Methyl isatin β-thiosemicarbazone-copper complex inhibits the RNA-dependent DNA polymerase activity of Rous sarcoma virus (RSV), but not its ribonuclease H. activity. In addition, bovine pancreatic RNase and DNase are not inhibited by the complex.</p></div>\",\"PeriodicalId\":9177,\"journal\":{\"name\":\"Bioinorganic chemistry\",\"volume\":\"8 6\",\"pages\":\"Pages 535-540\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1978-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0006-3061(78)80007-6\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioinorganic chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0006306178800076\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinorganic chemistry","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0006306178800076","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
摘要
n -甲基isatin β-硫代氨基脲-铜络合物抑制劳斯肉瘤病毒(RSV) rna依赖性DNA聚合酶活性，但对核糖核酸酶h活性无抑制作用。此外，牛胰腺RNase和DNase不受该复合物的抑制。
N-Methyly Isatin β-thiosemicarbazone-Copper Complex Inhibits RNA-Dependent DNA Polymerase but not Ribunuclease rous Sarcoma Virus
N-Methyl isatin β-thiosemicarbazone-copper complex inhibits the RNA-dependent DNA polymerase activity of Rous sarcoma virus (RSV), but not its ribonuclease H. activity. In addition, bovine pancreatic RNase and DNase are not inhibited by the complex.
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