睡眠呼吸障碍与牙周炎之间的关系:一项荟萃分析。

IF 2.2 3区 医学
X Liu, Z Zhu, P Zhang
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引用次数: 0

摘要

背景:全身性炎症是睡眠呼吸障碍(SDB)和牙周炎的一个特征。然而,SDB与牙周炎之间的关系在以往的研究中并不一致。为了充分评价上述关联,我们进行了meta分析。材料和方法:通过检索PubMed、Embase、Web of Science、万方和CNKI数据库确定与meta分析目的相关的观察性研究。仅纳入经客观多导睡眠图检查诊断为SDB的研究。使用随机效应模型对结果进行分析,该模型纳入了研究之间的潜在异质性。结果:10项横断面研究或病例对照研究共纳入43,296名参与者。合并结果显示,SDB与牙周炎有显著相关性(优势比[OR]: 1.83, 95%可信区间[CI]: 1.52 ~ 2.20, I2 = 40%, p < 0.001)。敏感性分析显示与严重牙周炎的相关性一致(OR: 1.39, 95% CI: 1.20 ~ 1.61, I2 = 0%, p < 0.001)。亚组分析显示,轻度(OR: 1.66, p < 0.001)、中度(OR: 2.23, p = 0.009)和重度SDB (OR: 2.66, p < 0.001)患者的结果一致。此外,在亚洲和非亚洲研究中,在横断面和病例对照研究中,在单变量和多变量回归模型研究中,以及在不同质量评分的研究中,SDB与牙周炎的相关性是一致的(亚组效应p均< 0.05)。结论:多导睡眠图确诊的SDB与成人牙周炎相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Association between sleep-disordered breathing and periodontitis: a meta-analysis.

Association between sleep-disordered breathing and periodontitis: a meta-analysis.

Association between sleep-disordered breathing and periodontitis: a meta-analysis.

Association between sleep-disordered breathing and periodontitis: a meta-analysis.

Background: Systemic inflammation is a feature of sleep-disordered breathing (SDB) as well as periodontitis. The association between SDB and periodontitis, however, has been inconsistent in previous studies. In order to fully evaluate the above association, we conducted a meta-analysis.

Material and methods: Observational studies related to the aim of the meta-analysis were identified by search of PubMed, Embase, Web of Science, Wanfang, and CNKI databases. Only studies with SDB diagnosed with the objective polysomnography examination were included. The results were analyzed using a random-effects model that incorporated potential heterogeneity between studies.

Results: Ten cross-sectional or case-control studies with 43,296 participants contributed to the meta-analysis. Pooled results showed that SDB was significantly associated with periodontitis (odds ratio [OR]: 1.83, 95% confidence interval [CI]: 1.52 to 2.20, I2 = 40%, p < 0.001). Sensitivity analysis showed consistent association for severe periodontitis (OR: 1.39, 95% CI: 1.20 to 1.61, I2 = 0%, p < 0.001). Subgroup analyses showed consistent results in patients with mild (OR: 1.66, p < 0.001), moderate (OR: 2.23, p = 0.009), and severe SDB (OR: 2.66, p < 0.001). Moreover, the association between SDB and periodontitis was consistent in Asian and non-Asian studies, in cross-sectional and case-control studies, in studies with univariate and multivariate regression models, and in studies with different quality scores (p for subgroup effects all < 0.05).

Conclusions: Polysomnography confirmed diagnosis of SDB is associated with periodontitis in adult population.

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来源期刊
CiteScore
4.50
自引率
0.00%
发文量
52
期刊介绍: 1. Oral Medicine and Pathology: Clinicopathological as well as medical or surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, as well as orofacial neurological disorders, and systemic conditions with an impact on the oral cavity. 2. Oral Surgery: Surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, teeth, implants, oral surgical procedures. Surgical management of diseases affecting head and neck areas. 3. Medically compromised patients in Dentistry: Articles discussing medical problems in Odontology will also be included, with a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients. 4. Implantology 5. Periodontology
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