预测新生儿和儿科重症监护病房手术部位感染的评分系统:初步研究。

IF 0.6 Q4 SURGERY
Leecarlo Lumban Gaol
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引用次数: 0

摘要

背景:手术部位感染(SSI)占发病率的很大一部分,每年2700万例手术中有50万例。一些研究者发现,导致手术创面感染的因素有细菌污染物的数量、细菌的毒力、手术创面周围的微环境和宿主的免疫系统。目的:探讨新生儿和儿科重症监护病房手术部位感染的危险因素,并将其应用于新生儿和儿科重症监护病房的危险指数。方法:对2018年1月至2019年7月在塔拉干总医院进行的SSI危险因素进行队列回顾性研究。采用卡方检验对不同因素进行分析,采用多元二元logistic回归模型对SSI的独立危险因素进行检验。结果:179例患者符合纳入标准。NICU 66例,PICU 113例。双因素分析显示,SSI与病房类型、手术室温度、围手术期败血症、住院时间、洗必泰使用相关(p < 0.05)。多变量分析确定了与SSI发生相关的三个独立参数:手术室温度(优势比[OR] 12,510;95%置信区间[CI] 4,198, 37,279;术中,0.001);围手术期败血症(OR 6424;95% ci 2221 18581;P = 0.001);使用洗必泰洗浴(OR 35,751);95%可信区间8,627,148,164;术中,0.001)。结论:根据这三个独立的参数,我们推荐对术后nicu和picu患者的SSI进行预后评分,这些患者仍需要进行诊断、效度和信度测试,以改善患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SCORING SYSTEM FOR PREDICTED SURGICAL-SITE INFECTION IN NEONATES AND PEDIATRIC INTENSIVE CARE UNIT: A PRELIMINARY STUDY.

Background: Surgical-site infections (SSI) account for a large portion of morbidity with the rate of 500,000 cases per year from 27 million surgeries. Some researchers found that factors contributing to surgical wound infections are the number of bacteria contaminants, the bacterias virulence, the micro-environment around the surgical wound, and the immune system of the host.

Objective: To account the risk factors for surgical-site infections in neonatal and pediatric intensive care unit and apply them in a risk index for neonates and pediatrics in critical care unit.

Method: A cohort retrospective study was initiated to investigate risk factors for SSI at Tarakan General Hospital from January 2018 to July 2019. The different factors then analyzed with chi-square test, whereas the multivariate binary logistic regression model was used to examine independent risk factors for SSI.

Result: A total of 179 patients met the inclusion criteria. There were 66 patients in NICU and 113 in PICU. Bivariate analysis showed that SSI was associated with type of ward, operating room temperature, perioperative septicemia, length of stay, and the use of chlorhexidine bath-washing (p<0.05). Multivariate analysis identified three independent parameters correlating with the occurance of SSI: operating room temperature (odds ratio [OR] 12,510; 95% confidence interval [CI] 4,198 37,279; P<0.001); perioperative septicemia (OR 6,424; 95% CI 2,221 18,581; P=0.001); and the use of chlorhexidine bath-washing (OR 35,751; 95% CI 8,627 148,164; P<0.001).

Conclusion: From these three independent paramaters, we recommend a prognostic scoring for SSI in post operative NICUs and PICUs patients that still need another diagnostic, validity and realibility test to improve patients outcome.

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