如何将伦理融入实验室研究。

IF 2.8 1区 哲学 Q1 MEDICAL ETHICS
Paola Buedo, Idalina Odziemczyk, Jolanta Perek-Białas, Marcin Waligora
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引用次数: 0

摘要

生物技术中与健康有关的创新需要预见潜在的生物伦理影响。在这篇文章中,我们提出了一种策略,将伦理问题纳入到一群在实验室阶段从事基因治疗和再生医学研究的早期研究人员中。我们与在生物技术实验室工作的早期研究人员举行了一系列焦点小组会议。目的是反思他们自身工作所面临的生物伦理挑战,促进研究伦理与实验室实践的结合。通过研究人员在会议前后填写的调查问卷以及对焦点小组内容的分析,对活动进行了评估。焦点小组系列活动的结果是,所有参与者都改变了对与其计划的研究有关的伦理问题的看法,提高了对研究伦理进行反思和辩论的能力,并增强了对自身研究活动中的伦理问题的认识。半数参与者对自己的研究工作进行了调整。这项研究为在实验室研究中植入伦理和加强责任提供了一个具体的策略。这是一种可以 "现场 "和 "实时 "进行伦理反思的策略,是对研究程序开始前对研究方案进行伦理评估这一传统策略的补充。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
How to embed ethics into laboratory research.

Health-related innovation in biotechnology requires anticipating potential bioethical implications. In this article, we present a strategy to embed ethics in a group of early-stage researchers performing research in gene therapy and regenerative medicine in the laboratory phase. We conducted a series of focus group meetings with early-stage researchers who work in biotechnology laboratories. The objective was to reflect on the bioethical challenges of their own work and to promote the integration of research ethics with laboratory practice. The activity was assessed with questionnaires completed by the researchers before and after the meetings, and the analyses of the focus groups' content. As a result of the focus group series, all participants changed their perspectives about ethical issues regarding their planned research, developed the ability to reflect and debate on research ethics and had increased awareness of ethical issues in their own research activities. Half of them made changes in their research work. The study provides a concrete strategy to embed ethics and to strengthen responsibility in laboratory research. It is a strategy that allows to perform ethics reflection "on site" and in "real time" and complements the classic strategy of ethics assessment of the research protocol before starting the research procedure.

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来源期刊
CiteScore
4.90
自引率
14.70%
发文量
49
审稿时长
>12 weeks
期刊介绍: Accountability in Research: Policies and Quality Assurance is devoted to the examination and critical analysis of systems for maximizing integrity in the conduct of research. It provides an interdisciplinary, international forum for the development of ethics, procedures, standards policies, and concepts to encourage the ethical conduct of research and to enhance the validity of research results. The journal welcomes views on advancing the integrity of research in the fields of general and multidisciplinary sciences, medicine, law, economics, statistics, management studies, public policy, politics, sociology, history, psychology, philosophy, ethics, and information science. All submitted manuscripts are subject to initial appraisal by the Editor, and if found suitable for further consideration, to peer review by independent, anonymous expert referees.
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