我该留下还是走?细胞器基因组中的基因保留。

IF 9 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Cell Systems Pub Date : 2022-11-16 DOI:10.1016/j.cels.2022.10.006

Lantana K Grub, Nikita Tsyba, Maulik R Patel

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引用次数: 0

摘要

线粒体和质体保留了它们自己的小而重要的基因组。然而，决定基因是保留在细胞器DNA中还是输出到“宿主”核基因组的进化压力尚不清楚。《细胞系统》上的一项新研究利用生物信息学数据和建模来确定决定细胞器基因保留的普遍“规则”，解决了这一知识差距。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Should I stay, or should I go? Gene retention in organellar genomes.

Mitochondria and plastids retain their own small but essential genomes. However, the evolutionary pressures that determine whether a gene is retained in organellar DNA or exported to the "host" nuclear genome remain unclear. A new study in Cell Systems addresses this knowledge gap using bioinformatic data and modeling to identify universal "rules" that determine organellar gene retention.

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来源期刊

Cell Systems Medicine-Pathology and Forensic Medicine

CiteScore

16.50

自引率

1.10%

发文量

审稿时长

42 days

期刊介绍： In 2015, Cell Systems was founded as a platform within Cell Press to showcase innovative research in systems biology. Our primary goal is to investigate complex biological phenomena that cannot be simply explained by basic mathematical principles. While the physical sciences have long successfully tackled such challenges, we have discovered that our most impactful publications often employ quantitative, inference-based methodologies borrowed from the fields of physics, engineering, mathematics, and computer science. We are committed to providing a home for elegant research that addresses fundamental questions in systems biology.