Christoph Leisser, Manuel Ruiss, Caroline Pilwachs, Oliver Findl
{"title":"一项前瞻性随机试验:ILM瓣转位与经典ILM剥离治疗中小黄斑孔的对比。","authors":"Christoph Leisser, Manuel Ruiss, Caroline Pilwachs, Oliver Findl","doi":"10.1007/s00717-022-00515-y","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The aim of the present study was to compare macular hole closure rates of patients with small and medium-sized macular holes who underwent vitrectomy with internal limiting membrane (ILM) peeling combined with ILM flap transposition over the macular hole, compared with classic ILM peeling.</p><p><strong>Methods: </strong>This prospective randomized trial was designed as a pilot study with two groups: ILM peeling with ILM flap transposition over the macular hole vs. classic ILM peeling.</p><p><strong>Results: </strong>Among 20 patients recruited, complete analysis could be performed for 16 patients. The macular hole closure rates were 100% in both groups, without significant differences with respect to postsurgical subfoveal hyporeflective zones (<i>p</i> = 1.0, Fisher's exact test), postsurgical visual acuity (<i>p</i> = 0.7, <i>t</i>-test), and postsurgical irregularities of the ellipsoid zone (<i>p</i> = 1.0, Fisher's exact test).</p><p><strong>Conclusion: </strong>Vitrectomy with ILM peeling combined with ILM flap transposition over the macular hole and classic ILM peeling are both successful methods for the repair of macular holes of small and medium size and are associated with comparable outcomes.</p>","PeriodicalId":21826,"journal":{"name":"Spektrum der Augenheilkunde","volume":"37 1","pages":"9-14"},"PeriodicalIF":0.2000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864214/pdf/","citationCount":"1","resultStr":"{\"title\":\"ILM peeling with ILM flap transposition vs. classic ILM peeling for small and medium macula holes-a prospective randomized trial.\",\"authors\":\"Christoph Leisser, Manuel Ruiss, Caroline Pilwachs, Oliver Findl\",\"doi\":\"10.1007/s00717-022-00515-y\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The aim of the present study was to compare macular hole closure rates of patients with small and medium-sized macular holes who underwent vitrectomy with internal limiting membrane (ILM) peeling combined with ILM flap transposition over the macular hole, compared with classic ILM peeling.</p><p><strong>Methods: </strong>This prospective randomized trial was designed as a pilot study with two groups: ILM peeling with ILM flap transposition over the macular hole vs. classic ILM peeling.</p><p><strong>Results: </strong>Among 20 patients recruited, complete analysis could be performed for 16 patients. The macular hole closure rates were 100% in both groups, without significant differences with respect to postsurgical subfoveal hyporeflective zones (<i>p</i> = 1.0, Fisher's exact test), postsurgical visual acuity (<i>p</i> = 0.7, <i>t</i>-test), and postsurgical irregularities of the ellipsoid zone (<i>p</i> = 1.0, Fisher's exact test).</p><p><strong>Conclusion: </strong>Vitrectomy with ILM peeling combined with ILM flap transposition over the macular hole and classic ILM peeling are both successful methods for the repair of macular holes of small and medium size and are associated with comparable outcomes.</p>\",\"PeriodicalId\":21826,\"journal\":{\"name\":\"Spektrum der Augenheilkunde\",\"volume\":\"37 1\",\"pages\":\"9-14\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864214/pdf/\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Spektrum der Augenheilkunde\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s00717-022-00515-y\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spektrum der Augenheilkunde","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00717-022-00515-y","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
ILM peeling with ILM flap transposition vs. classic ILM peeling for small and medium macula holes-a prospective randomized trial.
Background: The aim of the present study was to compare macular hole closure rates of patients with small and medium-sized macular holes who underwent vitrectomy with internal limiting membrane (ILM) peeling combined with ILM flap transposition over the macular hole, compared with classic ILM peeling.
Methods: This prospective randomized trial was designed as a pilot study with two groups: ILM peeling with ILM flap transposition over the macular hole vs. classic ILM peeling.
Results: Among 20 patients recruited, complete analysis could be performed for 16 patients. The macular hole closure rates were 100% in both groups, without significant differences with respect to postsurgical subfoveal hyporeflective zones (p = 1.0, Fisher's exact test), postsurgical visual acuity (p = 0.7, t-test), and postsurgical irregularities of the ellipsoid zone (p = 1.0, Fisher's exact test).
Conclusion: Vitrectomy with ILM peeling combined with ILM flap transposition over the macular hole and classic ILM peeling are both successful methods for the repair of macular holes of small and medium size and are associated with comparable outcomes.
期刊介绍：
"Spektrum der Augenheilkunde" is an educational journal for ophthalmologists. It is published six times per year and presents reviews, original papers, editorials, case studies and analyses surrounding technical innovations in ophthalmology. Letters to the editor, guest commentaries, book reviews, literature overviews, product information and a congress calendar complete the range of its contents. Thus, "Spektrum der Augenheilkunde" keeps ophthalmologists up-to-date on current developments, both practice-relevant and research-related. The editorial board and its editorial advisors guarantee the high quality of publications and a broad, well-balanced choice of published topics. Topics of interest: Complete range of ophthalmology; Ethical standards; Declaration of Helsinki, Informed consent, Animal rights
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
