体质指数组与代谢合并症与医疗保健和药物费用之间的关系:芬兰全国生物库和登记研究

Q2 Medicine
Aino Vesikansa, Juha Mehtälä, Katja Mutanen, Annamari Lundqvist, Tiina Laatikainen, Tero Ylisaukko-Oja, Tero Saukkonen, Kirsi H Pietiläinen
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引用次数: 1

摘要

背景:肥胖症的日益流行给全世界的个人和社会带来了巨大的成本负担。目的:在这项具有全国代表性的研究中,研究了芬兰人群中体重指数(BMI)组与代谢合并症(MetC)数量与总直接成本之间的关系。研究设计、环境和参与者:研究队列包括5587名BMI≥18.5 kg/m2的成年人,他们参加了芬兰健康与福利研究所(Finnish Institute for health and Welfare)进行的FinHealth 2017健康检查调查。卫生保健资源利用(HCRU)和药品采购数据收集自国家卫生保健和药品登记册。主要结局指标:主要结局指标为总直接费用(原发性和继发性HCRU费用和处方药费用)。结果:与正常体重相比,I级(BMI 30.0-34.9 kg/m2)和II - III级(BMI≥35.0 kg/m2)肥胖与年龄和性别调整后的直接成本分别高出43%和40%,主要是由于高BMI组的合并症急剧增加。在所有BMI组中,BMI≥2的个体占总研究人群的39%,占总成本的60%。结论:要控制肥胖的费用负担,治疗应与其他慢性疾病同等考虑,治疗决策应考虑bmi≥30.0 kg/m2。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The association between body mass index groups and metabolic comorbidities with healthcare and medication costs: a nationwide biobank and registry study in Finland.

The association between body mass index groups and metabolic comorbidities with healthcare and medication costs: a nationwide biobank and registry study in Finland.

The association between body mass index groups and metabolic comorbidities with healthcare and medication costs: a nationwide biobank and registry study in Finland.

The association between body mass index groups and metabolic comorbidities with healthcare and medication costs: a nationwide biobank and registry study in Finland.

Background: The increasing prevalence of obesity imposes a significant cost burden on individuals and societies worldwide.

Objective: In this nationally representative study, the association between body mass index (BMI) groups and the number of metabolic comorbidities (MetC) with total direct costs was investigated in the Finnish population.

Study design, setting, and participants: The study cohort included 5,587 adults with BMI ≥18.5 kg/m2 who participated in the cross-sectional FinHealth 2017 health examination survey conducted by the Finnish Institute for Health and Welfare. Data on healthcare resource utilization (HCRU) and drug purchases were collected from national healthcare and drug registers.

Main outcome measure: The primary outcome was total direct costs (costs of primary and secondary HCRU and prescription medications).

Results: Class I (BMI 30.0-34.9 kg/m2) and class II - III (BMI ≥35.0 kg/m2) obesity were associated with 43% and 40% higher age- and sex-adjusted direct costs, respectively, compared with normal weight, mainly driven by a steeply increased comorbidity in the higher BMI groups. In all BMI groups combined, individuals with ≥2 MetCs comprised 39% of the total study population and 60% of the total costs.

Conclusion: To manage the cost burden of obesity, treatment should be given equal consideration as other chronic diseases, and BMIs ≥30.0 kg/m2 should be considered in treatment decisions.

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