利用尸体椎间盘评估增强型功率等离子体发生器的切除效率和安全性。

IF 3.2 4区 医学 Q2 ENGINEERING, BIOMEDICAL
Biomedical Engineering Letters Pub Date : 2022-12-19 eCollection Date: 2023-02-01 DOI:10.1007/s13534-022-00253-9
Youngki Hong, Sung-Young Yoon, Sangho Sohn, Nack Hwan Kim, Yushin Kim, Sangheon Lee
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引用次数: 0

摘要

等离子能量已被用于对脊柱问题进行微创介入治疗。然而,这种手术的适应症有限,主要是因为其切除范围较小。为了克服这一问题,我们设计了增强型等离子能量装置。该设备旨在通过改变电极排列和增强最大电功率来最大限度地扩大切除范围。本研究旨在评估这种新设计的经皮椎间盘减压等离子发生器的效率和安全性。我们在 C 臂透视引导下,使用增强型等离子体在不同电压下对 7 个新鲜人体尸体腰椎标本进行了椎间盘内手术。结果发现,切除区域的体积与应用的电功率大小成正比。特别是在高功率条件下,经过 500 秒的处理后,几乎整个髓核都被清除了。产生的等离子体密度也随着给定电功率的增加而增加。温度上升的最高水平并未超过导致椎间盘胶原组织变性的水平。组织病理学检查也表明,周围的神经组织没有受到热损伤。总之,我们推测这种新设计的增强型等离子体发生器的概念可用于去除巨大的椎间盘材料,而不会对邻近的目标组织造成热损伤或结构损伤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of the resection efficiency and safety of an enhanced power plasma generator using cadaveric intervertebral discs.

Plasma energy has been used to provide minimally invasive interventional treatment for spinal problems. However, this procedure has been used for limited indications mainly because of its small resection range. To overcome this problem, we designed the enhanced power plasma device. This device seeks to maximize the resection area by modifying the electrode arrangement and enhancing the maximum electric power. The purpose of this study is to assess the efficiency and safety of this newly designed plasma generator, a device for percutaneous disc decompression. We performed an intradiscal procedure on 7 fresh human cadaver lumbar spine specimens using the enhanced power plasma under C-arm fluoroscopic guidance at various voltages. As a result, the volume of the removed area was proportional to the applied magnitude of the electric power level. In particular, under the high-power level condition after 500 s treatment, nearly the entire nucleus pulposus was eliminated. The generated plasma density also tends to grow along with the given electric power. The highest level of temperature rise did not exceed the level that would lead to degeneration in the collagen tissue of the intervertebral disc. Histopathologic examination also demonstrated that there was no thermal damage to the surrounding neural tissues. In conclusion, we speculate that the concepts of this newly designed enhanced plasma generator could be applied to remove huge disc materials without thermal or structural damage to the adjacent target tissues in future spine clinics.

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来源期刊
Biomedical Engineering Letters
Biomedical Engineering Letters ENGINEERING, BIOMEDICAL-
CiteScore
6.80
自引率
0.00%
发文量
34
期刊介绍: Biomedical Engineering Letters (BMEL) aims to present the innovative experimental science and technological development in the biomedical field as well as clinical application of new development. The article must contain original biomedical engineering content, defined as development, theoretical analysis, and evaluation/validation of a new technique. BMEL publishes the following types of papers: original articles, review articles, editorials, and letters to the editor. All the papers are reviewed in single-blind fashion.
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