在COVID-19患者侵袭性真菌感染即将增加的情况下,印度的抗真菌药物短缺:迫在眉睫的危机

Behram Khan Ghazi, Usman Zahid, Muhammad Abdullah Usman, Zohra Kazmi, Reem Hunain, Mehr Muhammad Adeel Riaz, Osman Kamal Osman Elmahi, Mohammad Yasir Essar, Mohammad Mehedi Hasan
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引用次数: 0

摘要

在第二波COVID-19大流行中,真菌感染的广泛流行可能是由于普遍和不明智地使用类固醇以及病毒的免疫抑制性。然而,这些真菌感染也意味着抗真菌药物的使用增加,从而危及其供应。两性霉素B是毛霉病的一线药物,毛霉病在第二波期间被宣布为印度的流行病。随着毒品需求的增加,制造和供应大量毒品以及通过建立黑市、传播虚假信息和不谨慎使用来进行剥削的挑战也随之而来。最重要的是在全国范围内准备充足的供应,在需求时期实施生产和供应大量药物的安全规定,并使它们以合理的价格获得。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antifungal Drugs Shortage in India amidst Looming Increase in Invasive Fungal Infections among COVID-19 Patients: An Impending Crisis.

The widespread prevalence of fungal infections in the second wave of COVID-19 pandemic could be owed to ubiquitous and injudicious use of steroids and immunosuppressive nature of the virus. However, these fungal infections also meant increased use of antifungal drugs, hence endangering their supply. Amphotericin B is the first line drug for mucormycosis which was declared as an epidemic in India during the second wave. With the increasing demand of the drug, came challenges to manufacture and supply large quantities of the drug and exploitation by creating a black market and spread of false information and imprudent usage. It is of utmost importance to be prepared with adequate supply all over the nation and implementing safety regulations in manufacturing and supply of large quantities of drugs during the demanding times and make them accessible at a reasonable rate.

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