接受疾病改善治疗的多发性硬化症患者的COVID-19疫苗接种:务实问题

IF 1.8 4区医学 Q2 Medicine

Drugs of today Pub Date : 2022-12-01 DOI:10.1358/dot.2022.58.12.3455368

Ioan-Alexandru Chirap-Mitulschi, Constantin Ghimus, Andreea Raluca Chirap-Mitulschi, Sabina Antonela Antoniu, Raluca Dragomir

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引用次数: 0

摘要

自2019年以来，SARS-COV-2大流行一直是一个全球公共卫生问题，报告病例超过4亿例，死亡600万人，并造成重大经济和社会损失。多发性硬化症(MS)等慢性疾病患者的重叠SARS-CoV-2感染会导致管理问题，特别是在接受疾病缓解疗法治疗的患者中。调查COVID-19疫苗接种有效性的研究表明，疫苗接种后免疫反应的变异性取决于患者的背景治疗，需要特别注意抗cd20治疗。本文对MS患者接受疾病改善治疗的COVID-19疫苗接种效果的现有数据进行了总结和批判性评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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COVID-19 vaccination in patients with multiple sclerosis receiving disease-modifying therapies: pragmatic issues.

The SARS-COV-2 pandemic has been a global public health problem since 2019, with over 400 million reported cases, 6 million deaths, and significant economic and social damage. Overlapping SARS-CoV-2 infection in patients with chronic diseases, such as multiple sclerosis (MS), causes management problems, especially in patients treated with disease-modifying therapies. Studies investigating COVID-19 vaccination effectiveness have shown variability in postvaccination immune response that depends on the patient's background treatment, and special attention is required for anti-CD20 therapies. Existing data on the efficacy of COVID-19 vaccination in patients with MS undergoing disease-modifying treatment are summarized and critically evaluated in this article.

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来源期刊

Drugs of today 医学-药学

CiteScore

3.90

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： An international, peer-reviewed journal publishing monographs on new products entering the market and review articles. Since its inception in 1965, Drugs of Today has established a reputation for excellence in providing physicians and other key healthcare professionals with practical, up-to-date monographs on recently approved and launched drugs.