慢性肾脏疾病的遗传易感性:联系、风险和管理。

IF 2.1 Q2 UROLOGY & NEPHROLOGY

International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI:10.2147/IJNRD.S363041

Hanny Sawaf, Tariku T Gudura, Sylvester Dorobisz, Dianne Sandy, Xiangling Wang, Shane A Bobart

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引用次数: 0

摘要

慢性肾脏疾病(CKD)在世界范围内与显著的发病率和死亡率相关。近年来，我们对CKD遗传原因的理解随着几种肾脏疾病的确定而显著扩大。这篇综述讨论了遗传性肾脏疾病的现状及其潜在的治疗方案。本文将重点综述囊性肾病、遗传相关性肾小球疾病、先天性肾脏和尿路异常(CAKUT)、常染色体显性-小管间质肾病(ADTKD)、遗传性肾结石和肾钙质沉着症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management.

查看原文本刊更多论文

Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management.

Chronic kidney disease (CKD) is associated with significant morbidity and mortality worldwide. In recent years, our understanding of genetic causes of CKD has expanded significantly with several renal conditions having been identified. This review discusses the current landscape of genetic kidney disease and their potential treatment options. This review will focus on cystic kidney disease, glomerular disease with genetic associations, congenital anomalies of kidneys and urinary tract (CAKUT), autosomal dominant-tubulointerstitial kidney disease (ADTKD), inherited nephrolithiasis and nephrocalcinosis.

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来源期刊

International Journal of Nephrology and Renovascular Disease UROLOGY & NEPHROLOGY-

CiteScore

3.90

自引率

5.00%

发文量

审稿时长

16 weeks

期刊介绍： International Journal of Nephrology and Renovascular Disease is an international, peer-reviewed, open-access journal focusing on the pathophysiology of the kidney and vascular supply. Epidemiology, screening, diagnosis, and treatment interventions are covered as well as basic science, biochemical and immunological studies. In particular, emphasis will be given to: -Chronic kidney disease- Complications of renovascular disease- Imaging techniques- Renal hypertension- Renal cancer- Treatment including pharmacological and transplantation- Dialysis and treatment of complications of dialysis and renal disease- Quality of Life- Patient satisfaction and preference- Health economic evaluations. The journal welcomes submitted papers covering original research, basic science, clinical studies, reviews & evaluations, guidelines, expert opinion and commentary, case reports and extended reports. The main focus of the journal will be to publish research and clinical results in humans but preclinical, animal and in vitro studies will be published where they shed light on disease processes and potential new therapies and interventions.